Integrative Epigenetic and Molecular Analysis Reveals a Novel Promoter for a New Isoform of the Transcription Factor TEAD4
TEAD4 is a transcription factor that plays a crucial role in the Hippo pathway by regulating the expression of genes related to proliferation and apoptosis. It is also involved in the maintenance and differentiation of the trophectoderm during pre- and post-implantation embryonic development. An alt...
Main Authors: | Shima Rashidiani, Gizaw Mamo, Benjámin Farkas, András Szabadi, Bálint Farkas, Veronika Uszkai, András Császár, Barbara Brandt, Kálmán Kovács, Marianna Pap, Tibor A. Rauch |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2024-02-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/25/4/2223 |
Similar Items
-
Comparative Assessment and High-Throughput Drug-Combination Profiling of TEAD-Palmitoylation Inhibitors in Hippo Pathway Deficient Mesothelioma
by: Lale Evsen, et al.
Published: (2023-11-01) -
Regulation of TEAD Transcription Factors in Cancer Biology
by: Hyunbin D. Huh, et al.
Published: (2019-06-01) -
Targeting the Hippo Pathway and Cancer through the TEAD Family of Transcription Factors
by: Jeffrey K. Holden, et al.
Published: (2018-03-01) -
TEADs serve as potential prognostic biomarkers and targets for human gastric cancer
by: Meng-huan Wang, et al.
Published: (2022-06-01) -
Discovery of a subtype-selective, covalent inhibitor against palmitoylation pocket of TEAD3
by: Tian Lu, et al.
Published: (2021-10-01)