Paraganglioma of the Recurrent Laryngeal Nerve
Background/Objective: Paragangliomas are rare neuroendocrine tumors that primarily arise in the adrenal gland. Head and neck paragangliomas comprise approximately 3% of all extra-adrenal paragangliomas, with a majority of those being found in the carotid body. Recurrent laryngeal nerve paraganglioma...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-01-01
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| Series: | AACE Clinical Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S237606052300127X |
| _version_ | 1797353584810000384 |
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| author | Thomas Dougherty, MD Gabriela Aitken, MD Richard Mack Harrell, MD Courtney Edwards, MD Sol V. Guerrero, MD David Bimston, MD |
| author_facet | Thomas Dougherty, MD Gabriela Aitken, MD Richard Mack Harrell, MD Courtney Edwards, MD Sol V. Guerrero, MD David Bimston, MD |
| author_sort | Thomas Dougherty, MD |
| collection | DOAJ |
| description | Background/Objective: Paragangliomas are rare neuroendocrine tumors that primarily arise in the adrenal gland. Head and neck paragangliomas comprise approximately 3% of all extra-adrenal paragangliomas, with a majority of those being found in the carotid body. Recurrent laryngeal nerve paragangliomas are exceedingly rare, with only 2 reported cases found in literature review. Here, we will present the third. Case Report: The patient is a 46-year-old woman with a history of a right thyroid nodule that had been previously biopsied benign with “paucity of diagnostic material.” Neck ultrasonography revealed a 7.4 cm nodule that demonstrated interval growth over a 2-year period, so it was recommended to proceed with right thyroid lobectomy and isthmusectomy. During resection, the recurrent laryngeal nerve appeared to “disappear” into the nodule, and it was resected along with the nodule to ensure proper margins. The nerve was reconstructed with an ansa cervicalis interposition graft, and the nodule was sent to pathology. Pathology revealed that the nodule was a 4.8 cm paraganglioma of the recurrent laryngeal nerve. Discussion: Paragangliomas of the head and neck are exceedingly rare. In patients who present with symptoms of dysphagia or dysphonia, further workup, including laryngoscopy and magnetic resonance imaging, could potentially identify and allow for appropriate planning for surgical resection. Conclusion: In rare cases, consideration of paraganglioma as part of the differential for thyroid nodules may assist with planning of surgery but will unlikely alter treatment. |
| first_indexed | 2024-03-08T13:33:08Z |
| format | Article |
| id | doaj.art-26d5422bfaed476db7005abefa924c99 |
| institution | Directory Open Access Journal |
| issn | 2376-0605 |
| language | English |
| last_indexed | 2024-03-08T13:33:08Z |
| publishDate | 2024-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | AACE Clinical Case Reports |
| spelling | doaj.art-26d5422bfaed476db7005abefa924c992024-01-17T04:17:01ZengElsevierAACE Clinical Case Reports2376-06052024-01-011012426Paraganglioma of the Recurrent Laryngeal NerveThomas Dougherty, MD0Gabriela Aitken, MD1Richard Mack Harrell, MD2Courtney Edwards, MD3Sol V. Guerrero, MD4David Bimston, MD5Department of Endocrine Surgery, Memorial Healthcare System, Hollywood, FloridaDepartment of Endocrine Surgery, Memorial Healthcare System, Hollywood, FloridaDepartment of Endocrine Surgery, Memorial Healthcare System, Hollywood, FloridaDepartment of Endocrine Surgery, Memorial Healthcare System, Hollywood, FloridaDivision of Endocrinology, Palm Beach Health Network Physician Group, Boca Raton, FloridaDepartment of Endocrine Surgery, Memorial Healthcare System, Hollywood, Florida; Address correspondence to Dr David Bimston, Department of Endocrine Surgery, Memorial Healthcare System, 1150N 35th Ave suite 200, Hollywood, FL.Background/Objective: Paragangliomas are rare neuroendocrine tumors that primarily arise in the adrenal gland. Head and neck paragangliomas comprise approximately 3% of all extra-adrenal paragangliomas, with a majority of those being found in the carotid body. Recurrent laryngeal nerve paragangliomas are exceedingly rare, with only 2 reported cases found in literature review. Here, we will present the third. Case Report: The patient is a 46-year-old woman with a history of a right thyroid nodule that had been previously biopsied benign with “paucity of diagnostic material.” Neck ultrasonography revealed a 7.4 cm nodule that demonstrated interval growth over a 2-year period, so it was recommended to proceed with right thyroid lobectomy and isthmusectomy. During resection, the recurrent laryngeal nerve appeared to “disappear” into the nodule, and it was resected along with the nodule to ensure proper margins. The nerve was reconstructed with an ansa cervicalis interposition graft, and the nodule was sent to pathology. Pathology revealed that the nodule was a 4.8 cm paraganglioma of the recurrent laryngeal nerve. Discussion: Paragangliomas of the head and neck are exceedingly rare. In patients who present with symptoms of dysphagia or dysphonia, further workup, including laryngoscopy and magnetic resonance imaging, could potentially identify and allow for appropriate planning for surgical resection. Conclusion: In rare cases, consideration of paraganglioma as part of the differential for thyroid nodules may assist with planning of surgery but will unlikely alter treatment.http://www.sciencedirect.com/science/article/pii/S237606052300127Xparagangliomarecurrent laryngeal nervethyroid nodule |
| spellingShingle | Thomas Dougherty, MD Gabriela Aitken, MD Richard Mack Harrell, MD Courtney Edwards, MD Sol V. Guerrero, MD David Bimston, MD Paraganglioma of the Recurrent Laryngeal Nerve AACE Clinical Case Reports paraganglioma recurrent laryngeal nerve thyroid nodule |
| title | Paraganglioma of the Recurrent Laryngeal Nerve |
| title_full | Paraganglioma of the Recurrent Laryngeal Nerve |
| title_fullStr | Paraganglioma of the Recurrent Laryngeal Nerve |
| title_full_unstemmed | Paraganglioma of the Recurrent Laryngeal Nerve |
| title_short | Paraganglioma of the Recurrent Laryngeal Nerve |
| title_sort | paraganglioma of the recurrent laryngeal nerve |
| topic | paraganglioma recurrent laryngeal nerve thyroid nodule |
| url | http://www.sciencedirect.com/science/article/pii/S237606052300127X |
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