On the Meaning of Medical Evidence Hierarchies

Evidence hierarchies are investigative strategies ordered with regard to the claimed strength of evidence. They have been used for a couple of decades in EBM, particularly in assessing evidence for treatment recommendations, but remain controversial. An under-investigated question is what the order...

Full description

Bibliographic Details
Main Author: Jesper Jerkert
Format: Article
Language:English
Published: University Library System, University of Pittsburgh 2021-04-01
Series:Philosophy of Medicine
Subjects:
Online Access:https://philmed.pitt.edu/philmed/article/view/31
_version_ 1811307357912694784
author Jesper Jerkert
author_facet Jesper Jerkert
author_sort Jesper Jerkert
collection DOAJ
description Evidence hierarchies are investigative strategies ordered with regard to the claimed strength of evidence. They have been used for a couple of decades in EBM, particularly in assessing evidence for treatment recommendations, but remain controversial. An under-investigated question is what the order in the hierarchy means. Four interpretations are discussed here. The two most credible are “typically stronger” or “ideally stronger.” The well-known GRADE framework seems to assume some “typically stronger” reading. Even if the interpretation of an evidence hierarchy were established, hierarchies are rather unhelpful for the task of evidence aggregation. Specifying the intended order relation may help to sort out disagreements.
first_indexed 2024-04-13T09:02:59Z
format Article
id doaj.art-26ddbe2275f74f008053dfd96816b23f
institution Directory Open Access Journal
issn 2692-3963
language English
last_indexed 2024-04-13T09:02:59Z
publishDate 2021-04-01
publisher University Library System, University of Pittsburgh
record_format Article
series Philosophy of Medicine
spelling doaj.art-26ddbe2275f74f008053dfd96816b23f2022-12-22T02:53:04ZengUniversity Library System, University of PittsburghPhilosophy of Medicine2692-39632021-04-012110.5195/pom.2021.3131On the Meaning of Medical Evidence HierarchiesJesper Jerkert0Department of Philosophy and History, Division of Philosophy, KTH Royal Institute of TechnologyEvidence hierarchies are investigative strategies ordered with regard to the claimed strength of evidence. They have been used for a couple of decades in EBM, particularly in assessing evidence for treatment recommendations, but remain controversial. An under-investigated question is what the order in the hierarchy means. Four interpretations are discussed here. The two most credible are “typically stronger” or “ideally stronger.” The well-known GRADE framework seems to assume some “typically stronger” reading. Even if the interpretation of an evidence hierarchy were established, hierarchies are rather unhelpful for the task of evidence aggregation. Specifying the intended order relation may help to sort out disagreements.https://philmed.pitt.edu/philmed/article/view/31evidence-based medicineevidence hierarchystrength of evidencequality of evidenceorder relationevidence aggregationlexicographic orderinggradeceteris paribusrctobservational study
spellingShingle Jesper Jerkert
On the Meaning of Medical Evidence Hierarchies
Philosophy of Medicine
evidence-based medicine
evidence hierarchy
strength of evidence
quality of evidence
order relation
evidence aggregation
lexicographic ordering
grade
ceteris paribus
rct
observational study
title On the Meaning of Medical Evidence Hierarchies
title_full On the Meaning of Medical Evidence Hierarchies
title_fullStr On the Meaning of Medical Evidence Hierarchies
title_full_unstemmed On the Meaning of Medical Evidence Hierarchies
title_short On the Meaning of Medical Evidence Hierarchies
title_sort on the meaning of medical evidence hierarchies
topic evidence-based medicine
evidence hierarchy
strength of evidence
quality of evidence
order relation
evidence aggregation
lexicographic ordering
grade
ceteris paribus
rct
observational study
url https://philmed.pitt.edu/philmed/article/view/31
work_keys_str_mv AT jesperjerkert onthemeaningofmedicalevidencehierarchies