Usefulness of Skin Autofluorescence as a Biomarker of Acute Oxidative Stress in Young Male Japanese Long-Distance Runners: A Cross-Sectional Study
Chronic oxidative stress in long-distance runners adversely affects conditioning. It is important to objectively assess and monitor oxidative stress, but measuring oxidative stress can be invasive or require skill to measure. Therefore, this study aimed to verify whether skin autofluorescence (SAF),...
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MDPI AG
2022-11-01
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| Series: | Sports |
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| Online Access: | https://www.mdpi.com/2075-4663/10/11/180 |
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| author | Rei Fujiwara Natsume Anzai Motoyasu Ishikawa Atsuhiko Takahashi |
| author_facet | Rei Fujiwara Natsume Anzai Motoyasu Ishikawa Atsuhiko Takahashi |
| author_sort | Rei Fujiwara |
| collection | DOAJ |
| description | Chronic oxidative stress in long-distance runners adversely affects conditioning. It is important to objectively assess and monitor oxidative stress, but measuring oxidative stress can be invasive or require skill to measure. Therefore, this study aimed to verify whether skin autofluorescence (SAF), a non-invasive, rapid, and easily calculable metric for calculating advanced glycation end products (AGEs), is useful as an oxidative stress biomarker. The subjects were 50 young Japanese male long-distance runners (aged 20.2 ± 1.2 years); 35 average-sized male university students (aged 19.8 ± 1.1 years) served as controls. The interactions and relationships between SAF and plasma pentosidine and oxidative stress markers (reactive oxygen metabolite-derived compounds [d-ROMs], biological antioxidant potential [BAP], and the BAP/d-ROMs ratio) in runners were examined, and SAF in the runners and controls was compared. The results suggest that plasma pentosidine in runners is associated with oxidative stress markers and that it can assess oxidative stress. However, as SAF was not associated with oxidative stress markers, it was not validated as one. In future, clarifying the factors affecting SAF may also clarify the relationship between SAF, plasma pentosidine, and oxidative stress markers. |
| first_indexed | 2024-03-09T17:59:50Z |
| format | Article |
| id | doaj.art-26e1d526a13b4c8eadc865cfb129d8d2 |
| institution | Directory Open Access Journal |
| issn | 2075-4663 |
| language | English |
| last_indexed | 2024-03-09T17:59:50Z |
| publishDate | 2022-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sports |
| spelling | doaj.art-26e1d526a13b4c8eadc865cfb129d8d22023-11-24T10:00:30ZengMDPI AGSports2075-46632022-11-01101118010.3390/sports10110180Usefulness of Skin Autofluorescence as a Biomarker of Acute Oxidative Stress in Young Male Japanese Long-Distance Runners: A Cross-Sectional StudyRei Fujiwara0Natsume Anzai1Motoyasu Ishikawa2Atsuhiko Takahashi3Department of Food and Nutrition, Junior College, Nihon University, 2-31-145 Bunkyo-Cho, Mishima 411-8555, Shizuoka, JapanDepartment of Philosophy, Division of Humanities, Graduate School of Humanities, Osaka University, 1-5 Machikaneyama-Cho, Toyonaka 560-8532, Osaka, JapanDepartment of Food and Nutrition, Junior College, Nihon University, 2-31-145 Bunkyo-Cho, Mishima 411-8555, Shizuoka, JapanDepartment of Food and Nutrition, Junior College, Nihon University, 2-31-145 Bunkyo-Cho, Mishima 411-8555, Shizuoka, JapanChronic oxidative stress in long-distance runners adversely affects conditioning. It is important to objectively assess and monitor oxidative stress, but measuring oxidative stress can be invasive or require skill to measure. Therefore, this study aimed to verify whether skin autofluorescence (SAF), a non-invasive, rapid, and easily calculable metric for calculating advanced glycation end products (AGEs), is useful as an oxidative stress biomarker. The subjects were 50 young Japanese male long-distance runners (aged 20.2 ± 1.2 years); 35 average-sized male university students (aged 19.8 ± 1.1 years) served as controls. The interactions and relationships between SAF and plasma pentosidine and oxidative stress markers (reactive oxygen metabolite-derived compounds [d-ROMs], biological antioxidant potential [BAP], and the BAP/d-ROMs ratio) in runners were examined, and SAF in the runners and controls was compared. The results suggest that plasma pentosidine in runners is associated with oxidative stress markers and that it can assess oxidative stress. However, as SAF was not associated with oxidative stress markers, it was not validated as one. In future, clarifying the factors affecting SAF may also clarify the relationship between SAF, plasma pentosidine, and oxidative stress markers.https://www.mdpi.com/2075-4663/10/11/180advanced glycation end productsskin autofluorescencepentosidined-ROMsBAPBAP/d-ROMs ratio |
| spellingShingle | Rei Fujiwara Natsume Anzai Motoyasu Ishikawa Atsuhiko Takahashi Usefulness of Skin Autofluorescence as a Biomarker of Acute Oxidative Stress in Young Male Japanese Long-Distance Runners: A Cross-Sectional Study Sports advanced glycation end products skin autofluorescence pentosidine d-ROMs BAP BAP/d-ROMs ratio |
| title | Usefulness of Skin Autofluorescence as a Biomarker of Acute Oxidative Stress in Young Male Japanese Long-Distance Runners: A Cross-Sectional Study |
| title_full | Usefulness of Skin Autofluorescence as a Biomarker of Acute Oxidative Stress in Young Male Japanese Long-Distance Runners: A Cross-Sectional Study |
| title_fullStr | Usefulness of Skin Autofluorescence as a Biomarker of Acute Oxidative Stress in Young Male Japanese Long-Distance Runners: A Cross-Sectional Study |
| title_full_unstemmed | Usefulness of Skin Autofluorescence as a Biomarker of Acute Oxidative Stress in Young Male Japanese Long-Distance Runners: A Cross-Sectional Study |
| title_short | Usefulness of Skin Autofluorescence as a Biomarker of Acute Oxidative Stress in Young Male Japanese Long-Distance Runners: A Cross-Sectional Study |
| title_sort | usefulness of skin autofluorescence as a biomarker of acute oxidative stress in young male japanese long distance runners a cross sectional study |
| topic | advanced glycation end products skin autofluorescence pentosidine d-ROMs BAP BAP/d-ROMs ratio |
| url | https://www.mdpi.com/2075-4663/10/11/180 |
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