Dentinogenesis Imperfekta : Aspek Genetika Molekular, Klasifikasi dan Upaya Penanggulangannya
<p>Dentinogenesis Imperfecta (DI) is a hereditary simple autosomal dominant disorder showing abnormalities in the dentin of developing teeth and occuring at a rate of about 1 in 8000 births affecting both primary and secondary dentitions. The expression of DI shows a high penetrance and a low...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Faculty of Dentistry, Universitas Indonesia
2015-10-01
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| Series: | Journal of Dentistry Indonesia |
| Online Access: | http://jdentistry.ui.ac.id/index.php/JDI/article/view/814 |
| _version_ | 1818007248567271424 |
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| author | Elza Ibrahim Auerkari A. Surjadi S. Mangoendjaja |
| author_facet | Elza Ibrahim Auerkari A. Surjadi S. Mangoendjaja |
| author_sort | Elza Ibrahim Auerkari |
| collection | DOAJ |
| description | <p>Dentinogenesis Imperfecta (DI) is a hereditary simple autosomal dominant disorder showing abnormalities in the dentin of developing teeth and occuring at a rate of about 1 in 8000 births affecting both primary and secondary dentitions. The expression of DI shows a high penetrance and a low mutation rate. Two main types of DI appear to exist: type 1 which is the defect associate with osteogenesis imperfecta, and type II which is the classical hereditary opalescent dentin. The formerly proposed DI type III appears to be only a modified expression of the same gene as in the classical DI type II. This paper reviews molecular genetic aspects of DI.</p> |
| first_indexed | 2024-04-14T05:13:23Z |
| format | Article |
| id | doaj.art-26e32c1971f144d7802aac8c294554ab |
| institution | Directory Open Access Journal |
| issn | 1693-9697 2355-4800 |
| language | English |
| last_indexed | 2024-04-14T05:13:23Z |
| publishDate | 2015-10-01 |
| publisher | Faculty of Dentistry, Universitas Indonesia |
| record_format | Article |
| series | Journal of Dentistry Indonesia |
| spelling | doaj.art-26e32c1971f144d7802aac8c294554ab2022-12-22T02:10:28ZengFaculty of Dentistry, Universitas IndonesiaJournal of Dentistry Indonesia1693-96972355-48002015-10-0162313610.14693/jdi.v6i2.814708Dentinogenesis Imperfekta : Aspek Genetika Molekular, Klasifikasi dan Upaya PenanggulangannyaElza Ibrahim Auerkari0A. Surjadi1S. Mangoendjaja2Department of Oral Biology, Faculty of Dentistry, Universitas Indonesia, Jakarta 10430Department of Oral Biology, Faculty of Dentistry, Universitas Indonesia, Jakarta 10430Department of Oral Biology, Faculty of Dentistry, Universitas Indonesia, Jakarta 10430<p>Dentinogenesis Imperfecta (DI) is a hereditary simple autosomal dominant disorder showing abnormalities in the dentin of developing teeth and occuring at a rate of about 1 in 8000 births affecting both primary and secondary dentitions. The expression of DI shows a high penetrance and a low mutation rate. Two main types of DI appear to exist: type 1 which is the defect associate with osteogenesis imperfecta, and type II which is the classical hereditary opalescent dentin. The formerly proposed DI type III appears to be only a modified expression of the same gene as in the classical DI type II. This paper reviews molecular genetic aspects of DI.</p>http://jdentistry.ui.ac.id/index.php/JDI/article/view/814 |
| spellingShingle | Elza Ibrahim Auerkari A. Surjadi S. Mangoendjaja Dentinogenesis Imperfekta : Aspek Genetika Molekular, Klasifikasi dan Upaya Penanggulangannya Journal of Dentistry Indonesia |
| title | Dentinogenesis Imperfekta : Aspek Genetika Molekular, Klasifikasi dan Upaya Penanggulangannya |
| title_full | Dentinogenesis Imperfekta : Aspek Genetika Molekular, Klasifikasi dan Upaya Penanggulangannya |
| title_fullStr | Dentinogenesis Imperfekta : Aspek Genetika Molekular, Klasifikasi dan Upaya Penanggulangannya |
| title_full_unstemmed | Dentinogenesis Imperfekta : Aspek Genetika Molekular, Klasifikasi dan Upaya Penanggulangannya |
| title_short | Dentinogenesis Imperfekta : Aspek Genetika Molekular, Klasifikasi dan Upaya Penanggulangannya |
| title_sort | dentinogenesis imperfekta aspek genetika molekular klasifikasi dan upaya penanggulangannya |
| url | http://jdentistry.ui.ac.id/index.php/JDI/article/view/814 |
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