PD-L1: expression regulation

Programmed death-ligand 1 (PD-L1), expressed on the surface of tumor cells, can bind to programmed cell death-1 (PD-1) on T cells. The interaction of PD-1 and PD-L1 can inhibit T-cell responses by decreasing T-cell activity and accelerating their apoptosis. Various cancers express high levels of PD-...

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Bibliographic Details
Main Authors: Yu-Jie Zhou, Guoli Li, Jiyin Wang, Mengyuan Liu, Zihan Wang, Yu Song, Xulong Zhang, Xi Wang
Format: Article
Language:English
Published: Wolters Kluwer Health 2023-04-01
Series:Blood Science
Online Access:http://journals.lww.com/10.1097/BS9.0000000000000149

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