Circulating Myeloid Derived Suppressor Cells (MDSC) That Accumulate in Premalignancy Share Phenotypic and Functional Characteristics With MDSC in Cancer

Circulating Myeloid Derived Suppressor Cells (MDSC) That Accumulate in Premalignancy Share Phenotypic and Functional Characteristics With MDSC in Cancer

Myeloid derived suppressor cells (MDSC) are a heterogeneous population of immature myeloid cells that accumulate in circulation of cancer patients and at tumor sites where they suppress anti-tumor immunity. We previously reported that in a colon cancer prevention trial of a MUC1 vaccine tested in in...

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Bibliographic Details
Main Authors: Peiwen Ma, Pamela L. Beatty, John McKolanis, Randal Brand, Robert E. Schoen, Olivera J. Finn
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Immunology
Subjects:
colonic adenomas
intraductal papillary mucinous neoplasm (IPMN)
tumor antigen mucin 1
immunosurveillance
myeloid derived suppressor cells (MDSC)
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01401/full

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