Benign myoepithelioma of the hard palate: a clinical and histological diagnostic challenge. Case report and literature review
Introduction: Myoepithelioma (ME) is a rare salivary gland tumor. Constructed aroung a clinical case, this article aims to gather up up-to-date epidemiological, clinical and histological data about myoeptihelioma with emphasis on the diagnostic approach and differential diagnoses, paraclinical exams...
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| Format: | Article |
| Language: | English |
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EDP Sciences
2018-06-01
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| Series: | Journal of Oral Medicine and Oral Surgery |
| Subjects: | |
| Online Access: | https://www.jomos.org/articles/mbcb/full_html/2018/02/mbcb170053/mbcb170053.html |
| _version_ | 1818429765859672064 |
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| author | Maffi-Berthier Louis Le pelletier François Ejeil Anne-laure |
| author_facet | Maffi-Berthier Louis Le pelletier François Ejeil Anne-laure |
| author_sort | Maffi-Berthier Louis |
| collection | DOAJ |
| description | Introduction: Myoepithelioma (ME) is a rare salivary gland tumor. Constructed aroung a clinical case, this article aims to gather up up-to-date epidemiological, clinical and histological data about myoeptihelioma with emphasis on the diagnostic approach and differential diagnoses, paraclinical exams and the main histological features reported for its characterization. Observation: A 41-year-old female, presenting a 1-year slowly enlarging palatine nodule was referred to the Oral Pathology Consultation. Clinical data and paraclinic examination were non-specific. A thorough histological examination, comparing clinical data with cyto-architectural and immunostaining profile of the tumor allowed a positive diagnosis of ME. Discussion: The clinical aspect of ME is close from other more frequent tumors within the same areas. Accordingly, its discovery is often incidental and its diagnosis histological. ME display variable architecture and composition, requiring full tumor examination for proper diagnosis. When benign, ME act as mixed tumor regarding local extension, prognosis and recurrence. Malignant ME behaves as a low-grade malignant tumor with metastatic potential. Conclusion: Despite its rarity, ME should be hypothesized in front of a palatine nodule. Clinician and pathologist should be particularly cautious regarding nature, malignancy and follow-up of this tumor, since few data are up-to-now available. |
| first_indexed | 2024-12-14T15:22:43Z |
| format | Article |
| id | doaj.art-26e85159b13c442dbd70b1211c00fa28 |
| institution | Directory Open Access Journal |
| issn | 2608-1326 |
| language | English |
| last_indexed | 2024-12-14T15:22:43Z |
| publishDate | 2018-06-01 |
| publisher | EDP Sciences |
| record_format | Article |
| series | Journal of Oral Medicine and Oral Surgery |
| spelling | doaj.art-26e85159b13c442dbd70b1211c00fa282022-12-21T22:56:06ZengEDP SciencesJournal of Oral Medicine and Oral Surgery2608-13262018-06-01242818810.1051/mbcb/2017040mbcb170053Benign myoepithelioma of the hard palate: a clinical and histological diagnostic challenge. Case report and literature reviewMaffi-Berthier LouisLe pelletier François0Ejeil Anne-laureDepartment of Oral & ENT Pathology, Pitié-Salpêtrière Hospital, Department of Dermatology, Cochin-Port Royal HospitalIntroduction: Myoepithelioma (ME) is a rare salivary gland tumor. Constructed aroung a clinical case, this article aims to gather up up-to-date epidemiological, clinical and histological data about myoeptihelioma with emphasis on the diagnostic approach and differential diagnoses, paraclinical exams and the main histological features reported for its characterization. Observation: A 41-year-old female, presenting a 1-year slowly enlarging palatine nodule was referred to the Oral Pathology Consultation. Clinical data and paraclinic examination were non-specific. A thorough histological examination, comparing clinical data with cyto-architectural and immunostaining profile of the tumor allowed a positive diagnosis of ME. Discussion: The clinical aspect of ME is close from other more frequent tumors within the same areas. Accordingly, its discovery is often incidental and its diagnosis histological. ME display variable architecture and composition, requiring full tumor examination for proper diagnosis. When benign, ME act as mixed tumor regarding local extension, prognosis and recurrence. Malignant ME behaves as a low-grade malignant tumor with metastatic potential. Conclusion: Despite its rarity, ME should be hypothesized in front of a palatine nodule. Clinician and pathologist should be particularly cautious regarding nature, malignancy and follow-up of this tumor, since few data are up-to-now available.https://www.jomos.org/articles/mbcb/full_html/2018/02/mbcb170053/mbcb170053.htmlpathologyoralmyoepitheliomapalateneoplasms |
| spellingShingle | Maffi-Berthier Louis Le pelletier François Ejeil Anne-laure Benign myoepithelioma of the hard palate: a clinical and histological diagnostic challenge. Case report and literature review Journal of Oral Medicine and Oral Surgery pathology oral myoepithelioma palate neoplasms |
| title | Benign myoepithelioma of the hard palate: a clinical and histological diagnostic challenge. Case report and literature review |
| title_full | Benign myoepithelioma of the hard palate: a clinical and histological diagnostic challenge. Case report and literature review |
| title_fullStr | Benign myoepithelioma of the hard palate: a clinical and histological diagnostic challenge. Case report and literature review |
| title_full_unstemmed | Benign myoepithelioma of the hard palate: a clinical and histological diagnostic challenge. Case report and literature review |
| title_short | Benign myoepithelioma of the hard palate: a clinical and histological diagnostic challenge. Case report and literature review |
| title_sort | benign myoepithelioma of the hard palate a clinical and histological diagnostic challenge case report and literature review |
| topic | pathology oral myoepithelioma palate neoplasms |
| url | https://www.jomos.org/articles/mbcb/full_html/2018/02/mbcb170053/mbcb170053.html |
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