New Furanones from the Plant Endophytic Fungus Pestalotiopsis besseyi

New Furanones from the Plant Endophytic Fungus Pestalotiopsis besseyi

Pestalafuranones A–E (compounds 1–5), five new 2(5H)-furanones, have been isolated from cultures of an isolate of Pestalotiopsis besseyi. The structures of these compounds were elucidated mainly by analysis of their NMR spectroscopic data and HRESIMS experiments. Pestalaf...

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Bibliographic Details
Main Authors: Langjun Cui, Gang Ding, Yonggang Zhang, Liangdong Guo, Shuchun Liu, Haitao Liu
Format: Article
Language:English
Published: MDPI AG 2012-11-01
Series:Molecules
Subjects:
pestalafuranones A&#8211
E
endophytes
Pestalotiopsis besseyi
bioactivity
Online Access:http://www.mdpi.com/1420-3049/17/12/14015
Description
Summary:Pestalafuranones A–E (compounds 1–5), five new 2(5H)-furanones, have been isolated from cultures of an isolate of Pestalotiopsis besseyi. The structures of these compounds were elucidated mainly by analysis of their NMR spectroscopic data and HRESIMS experiments. Pestalafuranones A–C (compounds 1–3) displayed weak inhibitory effects against HIV-1 replication in C8166 cells, whereas pestalafuranones D (4) and E (5) showed moderate antifungal activity against the plant pathogens Verticillium dahiae and Alternaria longipes.
ISSN:1420-3049

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