A Novel Desloratadine-Benzoic Acid Co-Amorphous Solid: Preparation, Characterization, and Stability Evaluation

A Novel Desloratadine-Benzoic Acid Co-Amorphous Solid: Preparation, Characterization, and Stability Evaluation

Low physical stability is the limitation of the widespread use of amorphous drugs. The co-amorphous drug system is a new and emerging method for preparing a stable amorphous form. Co-amorphous is a single-phase amorphous multicomponent system consisting of two or more small molecules that are a comb...

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Bibliographic Details
Main Authors: Ahmad Ainurofiq, Rachmat Mauludin, Diky Mudhakir, Sundani Nurono Soewandhi
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Pharmaceutics
Subjects:
desloratadine
benzoic acid
co-amorphous
solubility
stability
melt-quenching
Online Access:http://www.mdpi.com/1999-4923/10/3/85

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