Feasibility and Effectiveness of a Preventive Care Program during the Compound Humanitarian Crisis and COVID-19 Pandemic in Venezuela
Effective preventive care programs are urgently needed during humanitarian crises, as has been especially obvious during the COVID-19 pandemic. A pragmatic trial was designed: hybridized intervention (Diabetes Prevention Program [DPP] + medical nutrition therapy + liquid diet [LD]; LD group) vs. DPP...
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MDPI AG
2022-02-01
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Series: | Nutrients |
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Online Access: | https://www.mdpi.com/2072-6643/14/5/939 |
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author | Juan P. González-Rivas María M. Infante-García Ramfis Nieto-Martinez Jeffrey I. Mechanick Goodarz Danaei |
author_facet | Juan P. González-Rivas María M. Infante-García Ramfis Nieto-Martinez Jeffrey I. Mechanick Goodarz Danaei |
author_sort | Juan P. González-Rivas |
collection | DOAJ |
description | Effective preventive care programs are urgently needed during humanitarian crises, as has been especially obvious during the COVID-19 pandemic. A pragmatic trial was designed: hybridized intervention (Diabetes Prevention Program [DPP] + medical nutrition therapy + liquid diet [LD]; LD group) vs. DPP only (DPP group). The participants were adults who were overweight/obese and at high risk of type 2 diabetes mellitus (T2DM). The LD consisted of a “homemade” milk- and fruit-juice-based beverage. Pandemic restrictions delayed the program by nine months, tripled the amount of time required for screening, and reduced the total sample to 60%. Eventually, 127 participants were randomized, and 94/127 participants (74.0%) completed the first phase. Participant dropout was influenced by migration, COVID-19 symptoms, education level, and socioeconomic status. In two months, the LD group lost 2.9 kg (<i>p</i> < 0.001) and the DPP group, 2.2 kg (<i>p</i> < 0.001) (between-group <i>p</i> = 0.170), with improvements in their cardiometabolic risk factors. At this stage, the DPP was shown to be feasible and effective, demonstrating weight loss with the improvement of cardiometabolic risk factors in a primary setting in Venezuela, a middle-income country with a chronic humanitarian crisis, during the COVID-19 pandemic. |
first_indexed | 2024-03-09T20:26:58Z |
format | Article |
id | doaj.art-26f5bb9c8d7a41748fc005f91dddcd17 |
institution | Directory Open Access Journal |
issn | 2072-6643 |
language | English |
last_indexed | 2024-03-09T20:26:58Z |
publishDate | 2022-02-01 |
publisher | MDPI AG |
record_format | Article |
series | Nutrients |
spelling | doaj.art-26f5bb9c8d7a41748fc005f91dddcd172023-11-23T23:32:07ZengMDPI AGNutrients2072-66432022-02-0114593910.3390/nu14050939Feasibility and Effectiveness of a Preventive Care Program during the Compound Humanitarian Crisis and COVID-19 Pandemic in VenezuelaJuan P. González-Rivas0María M. Infante-García1Ramfis Nieto-Martinez2Jeffrey I. Mechanick3Goodarz Danaei4Departments of Global Health and Population and Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA 02115, USAInternational Clinical Research Center (ICRC), St. Anne’s University Hospital (FNUSA) Brno, Pekařská 53, 656 91 Brno, Czech RepublicDepartments of Global Health and Population and Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA 02115, USAThe Marie-Josée and Henry R. Kravis Center for Cardiovascular Health at Mount Sinai Heart, Icahn School of Medicine at Mount Sinai, New York, NY 10028, USADepartments of Global Health and Population and Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA 02115, USAEffective preventive care programs are urgently needed during humanitarian crises, as has been especially obvious during the COVID-19 pandemic. A pragmatic trial was designed: hybridized intervention (Diabetes Prevention Program [DPP] + medical nutrition therapy + liquid diet [LD]; LD group) vs. DPP only (DPP group). The participants were adults who were overweight/obese and at high risk of type 2 diabetes mellitus (T2DM). The LD consisted of a “homemade” milk- and fruit-juice-based beverage. Pandemic restrictions delayed the program by nine months, tripled the amount of time required for screening, and reduced the total sample to 60%. Eventually, 127 participants were randomized, and 94/127 participants (74.0%) completed the first phase. Participant dropout was influenced by migration, COVID-19 symptoms, education level, and socioeconomic status. In two months, the LD group lost 2.9 kg (<i>p</i> < 0.001) and the DPP group, 2.2 kg (<i>p</i> < 0.001) (between-group <i>p</i> = 0.170), with improvements in their cardiometabolic risk factors. At this stage, the DPP was shown to be feasible and effective, demonstrating weight loss with the improvement of cardiometabolic risk factors in a primary setting in Venezuela, a middle-income country with a chronic humanitarian crisis, during the COVID-19 pandemic.https://www.mdpi.com/2072-6643/14/5/939type 2 diabetes mellitushumanitarian crisisprimary preventionCOVID-19 |
spellingShingle | Juan P. González-Rivas María M. Infante-García Ramfis Nieto-Martinez Jeffrey I. Mechanick Goodarz Danaei Feasibility and Effectiveness of a Preventive Care Program during the Compound Humanitarian Crisis and COVID-19 Pandemic in Venezuela Nutrients type 2 diabetes mellitus humanitarian crisis primary prevention COVID-19 |
title | Feasibility and Effectiveness of a Preventive Care Program during the Compound Humanitarian Crisis and COVID-19 Pandemic in Venezuela |
title_full | Feasibility and Effectiveness of a Preventive Care Program during the Compound Humanitarian Crisis and COVID-19 Pandemic in Venezuela |
title_fullStr | Feasibility and Effectiveness of a Preventive Care Program during the Compound Humanitarian Crisis and COVID-19 Pandemic in Venezuela |
title_full_unstemmed | Feasibility and Effectiveness of a Preventive Care Program during the Compound Humanitarian Crisis and COVID-19 Pandemic in Venezuela |
title_short | Feasibility and Effectiveness of a Preventive Care Program during the Compound Humanitarian Crisis and COVID-19 Pandemic in Venezuela |
title_sort | feasibility and effectiveness of a preventive care program during the compound humanitarian crisis and covid 19 pandemic in venezuela |
topic | type 2 diabetes mellitus humanitarian crisis primary prevention COVID-19 |
url | https://www.mdpi.com/2072-6643/14/5/939 |
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