Nonerosive gastroesophageal reflux disease and mild degree of esophagitis: Comparison of symptoms endoscopic, manometric and pH-metric patterns
<p>Abstract</p> <p>Background</p> <p>Our aim in the present study was to compare patients presenting with gastroesophageal reflux disease in the presence or absence of mild-grade esophagitis (grade I or II according to the Savary-Miller classification).</p> <p&...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2012-05-01
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| Series: | World Journal of Surgical Oncology |
| Subjects: | |
| Online Access: | http://www.wjso.com/content/10/1/84 |
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| author | Grande Michele Sileri Pierpaolo Attinà Grazia De Luca Elisabetta Ciano Paolo Ciangola Carolina Cadeddu Federica |
| author_facet | Grande Michele Sileri Pierpaolo Attinà Grazia De Luca Elisabetta Ciano Paolo Ciangola Carolina Cadeddu Federica |
| author_sort | Grande Michele |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>Our aim in the present study was to compare patients presenting with gastroesophageal reflux disease in the presence or absence of mild-grade esophagitis (grade I or II according to the Savary-Miller classification).</p> <p>Methods</p> <p>Between 2005 and 2007, 215 patients with gastroesophageal reflux disease (67 with reflux associated with grade I or II esophagitis and 148 without esophagitis) were evaluated at the Department of Surgery, University Hospital Tor Vergata, Rome, and were included in the present study. The evaluations consisted of clinical interviews, endoscopy of the high digestive tract, esophageal manometry and pH monitoring.</p> <p>Results</p> <p>There was no significant difference between the two groups with regard to age, sex or symptoms. The incidence of heartburn associated with noncardiac chest pain was greater in the esophagitis group than in the dysphagia group. The incidence of hiatal hernia was similar in both groups. Although the motor pattern was similar in both groups, the length of the abdominal esophagus was greater in patients without esophagitis (1.6 cm vs 1.1 cm; <it>P</it> < 0.05). The reflux pattern was nearly identical in both groups.</p> <p>Conclusions</p> <p>Gastroesophageal reflux without esophagitis must be regarded not as a milder form of the disease but as part of a single disease. Furthermore, these patients often demonstrate lower rates of symptom improvement after antireflux treatment in comparison with patients with erosive esophagitis. Therefore, further trials to assess the treatment algorithm for these patients are warranted.</p> |
| first_indexed | 2024-04-13T12:52:45Z |
| format | Article |
| id | doaj.art-26f73870248b43d5a24c59d15fe625f0 |
| institution | Directory Open Access Journal |
| issn | 1477-7819 |
| language | English |
| last_indexed | 2024-04-13T12:52:45Z |
| publishDate | 2012-05-01 |
| publisher | BMC |
| record_format | Article |
| series | World Journal of Surgical Oncology |
| spelling | doaj.art-26f73870248b43d5a24c59d15fe625f02022-12-22T02:46:09ZengBMCWorld Journal of Surgical Oncology1477-78192012-05-011018410.1186/1477-7819-10-84Nonerosive gastroesophageal reflux disease and mild degree of esophagitis: Comparison of symptoms endoscopic, manometric and pH-metric patternsGrande MicheleSileri PierpaoloAttinà GraziaDe Luca ElisabettaCiano PaoloCiangola CarolinaCadeddu Federica<p>Abstract</p> <p>Background</p> <p>Our aim in the present study was to compare patients presenting with gastroesophageal reflux disease in the presence or absence of mild-grade esophagitis (grade I or II according to the Savary-Miller classification).</p> <p>Methods</p> <p>Between 2005 and 2007, 215 patients with gastroesophageal reflux disease (67 with reflux associated with grade I or II esophagitis and 148 without esophagitis) were evaluated at the Department of Surgery, University Hospital Tor Vergata, Rome, and were included in the present study. The evaluations consisted of clinical interviews, endoscopy of the high digestive tract, esophageal manometry and pH monitoring.</p> <p>Results</p> <p>There was no significant difference between the two groups with regard to age, sex or symptoms. The incidence of heartburn associated with noncardiac chest pain was greater in the esophagitis group than in the dysphagia group. The incidence of hiatal hernia was similar in both groups. Although the motor pattern was similar in both groups, the length of the abdominal esophagus was greater in patients without esophagitis (1.6 cm vs 1.1 cm; <it>P</it> < 0.05). The reflux pattern was nearly identical in both groups.</p> <p>Conclusions</p> <p>Gastroesophageal reflux without esophagitis must be regarded not as a milder form of the disease but as part of a single disease. Furthermore, these patients often demonstrate lower rates of symptom improvement after antireflux treatment in comparison with patients with erosive esophagitis. Therefore, further trials to assess the treatment algorithm for these patients are warranted.</p>http://www.wjso.com/content/10/1/84Antireflux surgeryGastroesophageal reflux diseaseNonerosive reflux diseaseErosive esophagitis24-hour pH-metry |
| spellingShingle | Grande Michele Sileri Pierpaolo Attinà Grazia De Luca Elisabetta Ciano Paolo Ciangola Carolina Cadeddu Federica Nonerosive gastroesophageal reflux disease and mild degree of esophagitis: Comparison of symptoms endoscopic, manometric and pH-metric patterns World Journal of Surgical Oncology Antireflux surgery Gastroesophageal reflux disease Nonerosive reflux disease Erosive esophagitis 24-hour pH-metry |
| title | Nonerosive gastroesophageal reflux disease and mild degree of esophagitis: Comparison of symptoms endoscopic, manometric and pH-metric patterns |
| title_full | Nonerosive gastroesophageal reflux disease and mild degree of esophagitis: Comparison of symptoms endoscopic, manometric and pH-metric patterns |
| title_fullStr | Nonerosive gastroesophageal reflux disease and mild degree of esophagitis: Comparison of symptoms endoscopic, manometric and pH-metric patterns |
| title_full_unstemmed | Nonerosive gastroesophageal reflux disease and mild degree of esophagitis: Comparison of symptoms endoscopic, manometric and pH-metric patterns |
| title_short | Nonerosive gastroesophageal reflux disease and mild degree of esophagitis: Comparison of symptoms endoscopic, manometric and pH-metric patterns |
| title_sort | nonerosive gastroesophageal reflux disease and mild degree of esophagitis comparison of symptoms endoscopic manometric and ph metric patterns |
| topic | Antireflux surgery Gastroesophageal reflux disease Nonerosive reflux disease Erosive esophagitis 24-hour pH-metry |
| url | http://www.wjso.com/content/10/1/84 |
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