COVID-19 vaccination prevents a more severe course and treatment with complement inhibitors reduce worsening hemolysis during the Omicron pandemic in patients with PNH: a single-center study

COVID-19 vaccination prevents a more severe course and treatment with complement inhibitors reduce worsening hemolysis during the Omicron pandemic in patients with PNH: a single-center study

AbstractObjective Paroxysmal nocturnal hemoglobinuria (PNH) is a rare acquired disease characterized by chronic complement-mediated hemolysis. The concentrated outbreak of coronavirus disease 2019 (COVID-19) in China after 6 December 2022, provided an opportunity to observe the disease course of PNH...

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Bibliographic Details
Main Authors: Leyu Wang, Qinglin Hu, Yuan Yang, Miao Chen, Chen Yang, Bing Han
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Annals of Medicine
Subjects:
Paroxysmal nocturnal hemoglobinuria
omicron infection
Covid-19
hemolysis aggravation
complement inhibitor
vaccination
Online Access:https://www.tandfonline.com/doi/10.1080/07853890.2023.2274510

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