Control of Alphavirus Replication in Neurons

Sindbis virus causes age-dependent encephalomyelitis in mice. Young mice and immature neurons replicate the virus to high titers and die from infection while older mice and mature neurons restrict replication and survive infection. Studies to identify factors that affect maturation-dependent virus r...

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Bibliographic Details
Main Authors: Jane Yeh, Elizabeth Troisi, Rachy Abraham, Diane Griffin
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Proceedings
Subjects:
Online Access:https://www.mdpi.com/2504-3900/50/1/78