Correlation of Urine Loss after Catheter Removal and Early Continence in Men Undergoing Radical Prostatectomy
Background: To determine the correlation between urine loss in PAD-test after catheter removal, and early urinary continence (UC) in RP treated patients. Methods: Urine loss was measured by using a standardized, validated PAD-test within 24 h after removal of the transurethral catheter, and was grou...
| Main Authors: | , , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-11-01
|
| Series: | Current Oncology |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1718-7729/28/6/399 |
| _version_ | 1797505582663467008 |
|---|---|
| author | Benedikt Hoeh Felix Preisser Mike Wenzel Clara Humke Clarissa Wittler Jan L. Hohenhorst Maja Volckmann-Wilde Jens Köllermann Thomas Steuber Markus Graefen Derya Tilki Pierre I. Karakiewicz Andreas Becker Luis A. Kluth Felix K. H. Chun Philipp Mandel |
| author_facet | Benedikt Hoeh Felix Preisser Mike Wenzel Clara Humke Clarissa Wittler Jan L. Hohenhorst Maja Volckmann-Wilde Jens Köllermann Thomas Steuber Markus Graefen Derya Tilki Pierre I. Karakiewicz Andreas Becker Luis A. Kluth Felix K. H. Chun Philipp Mandel |
| author_sort | Benedikt Hoeh |
| collection | DOAJ |
| description | Background: To determine the correlation between urine loss in PAD-test after catheter removal, and early urinary continence (UC) in RP treated patients. Methods: Urine loss was measured by using a standardized, validated PAD-test within 24 h after removal of the transurethral catheter, and was grouped as a loss of <1, 1–10, 11–50, and >50 g of urine, respectively. Early UC (median: 3 months) was defined as the usage of no or one safety-pad. Uni- and multivariable logistic regression models tested the correlation between PAD-test results and early UC. Covariates consisted of age, BMI, nerve-sparing approach, prostate volume, and extraprostatic extension of tumor. Results: From 01/2018 to 03/2021, 100 patients undergoing RP with data available for a PAD-test and early UC were retrospectively identified. Ultimately, 24%, 47%, 15%, and 14% of patients had a loss of urine <1 g, 1–10 g, 11–50 g, and >50 g in PAD-test, respectively. Additionally, 59% of patients reported to be continent. In multivariable logistic regression models, urine loss in PAD-test predicted early UC (OR: 0.21 vs. 0.09 vs. 0.03; for urine loss 1–10 g vs. 11–50 g vs. >50 g, Ref: <1 g; all <i>p</i> < 0.05). Conclusions: Urine loss after catheter removal strongly correlated with early continence as well as a severity in urinary incontinence. |
| first_indexed | 2024-03-10T04:20:40Z |
| format | Article |
| id | doaj.art-26fd1e722dde4ca7b14a06327018f4ac |
| institution | Directory Open Access Journal |
| issn | 1198-0052 1718-7729 |
| language | English |
| last_indexed | 2024-03-10T04:20:40Z |
| publishDate | 2021-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Current Oncology |
| spelling | doaj.art-26fd1e722dde4ca7b14a06327018f4ac2023-11-23T07:50:33ZengMDPI AGCurrent Oncology1198-00521718-77292021-11-012864738474710.3390/curroncol28060399Correlation of Urine Loss after Catheter Removal and Early Continence in Men Undergoing Radical ProstatectomyBenedikt Hoeh0Felix Preisser1Mike Wenzel2Clara Humke3Clarissa Wittler4Jan L. Hohenhorst5Maja Volckmann-Wilde6Jens Köllermann7Thomas Steuber8Markus Graefen9Derya Tilki10Pierre I. Karakiewicz11Andreas Becker12Luis A. Kluth13Felix K. H. Chun14Philipp Mandel15Department of Urology, University Hospital Frankfurt, Goethe University Frankfurt am Main, 60323 Frankfurt am Main, GermanyDepartment of Urology, University Hospital Frankfurt, Goethe University Frankfurt am Main, 60323 Frankfurt am Main, GermanyDepartment of Urology, University Hospital Frankfurt, Goethe University Frankfurt am Main, 60323 Frankfurt am Main, GermanyDepartment of Urology, University Hospital Frankfurt, Goethe University Frankfurt am Main, 60323 Frankfurt am Main, GermanyDepartment of Urology, University Hospital Frankfurt, Goethe University Frankfurt am Main, 60323 Frankfurt am Main, GermanyCancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montréal Health Center, Montréal, QC H3T 1C5, CanadaDepartment of Urology, University Hospital Frankfurt, Goethe University Frankfurt am Main, 60323 Frankfurt am Main, GermanyDr. Senckenberg Institute of Pathology, University Hospital Frankfurt, 60590 Frankfurt am Main, GermanyMartini-Klinik Prostate Cancer Center, University Hospital Hamburg-Eppendorf, 20246 Hamburg, GermanyMartini-Klinik Prostate Cancer Center, University Hospital Hamburg-Eppendorf, 20246 Hamburg, GermanyMartini-Klinik Prostate Cancer Center, University Hospital Hamburg-Eppendorf, 20246 Hamburg, GermanyCancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montréal Health Center, Montréal, QC H3T 1C5, CanadaDepartment of Urology, University Hospital Frankfurt, Goethe University Frankfurt am Main, 60323 Frankfurt am Main, GermanyDepartment of Urology, University Hospital Frankfurt, Goethe University Frankfurt am Main, 60323 Frankfurt am Main, GermanyDepartment of Urology, University Hospital Frankfurt, Goethe University Frankfurt am Main, 60323 Frankfurt am Main, GermanyDepartment of Urology, University Hospital Frankfurt, Goethe University Frankfurt am Main, 60323 Frankfurt am Main, GermanyBackground: To determine the correlation between urine loss in PAD-test after catheter removal, and early urinary continence (UC) in RP treated patients. Methods: Urine loss was measured by using a standardized, validated PAD-test within 24 h after removal of the transurethral catheter, and was grouped as a loss of <1, 1–10, 11–50, and >50 g of urine, respectively. Early UC (median: 3 months) was defined as the usage of no or one safety-pad. Uni- and multivariable logistic regression models tested the correlation between PAD-test results and early UC. Covariates consisted of age, BMI, nerve-sparing approach, prostate volume, and extraprostatic extension of tumor. Results: From 01/2018 to 03/2021, 100 patients undergoing RP with data available for a PAD-test and early UC were retrospectively identified. Ultimately, 24%, 47%, 15%, and 14% of patients had a loss of urine <1 g, 1–10 g, 11–50 g, and >50 g in PAD-test, respectively. Additionally, 59% of patients reported to be continent. In multivariable logistic regression models, urine loss in PAD-test predicted early UC (OR: 0.21 vs. 0.09 vs. 0.03; for urine loss 1–10 g vs. 11–50 g vs. >50 g, Ref: <1 g; all <i>p</i> < 0.05). Conclusions: Urine loss after catheter removal strongly correlated with early continence as well as a severity in urinary incontinence.https://www.mdpi.com/1718-7729/28/6/399urinary incontinenceradical prostatectomypad-testincontinencefunctional outcome |
| spellingShingle | Benedikt Hoeh Felix Preisser Mike Wenzel Clara Humke Clarissa Wittler Jan L. Hohenhorst Maja Volckmann-Wilde Jens Köllermann Thomas Steuber Markus Graefen Derya Tilki Pierre I. Karakiewicz Andreas Becker Luis A. Kluth Felix K. H. Chun Philipp Mandel Correlation of Urine Loss after Catheter Removal and Early Continence in Men Undergoing Radical Prostatectomy Current Oncology urinary incontinence radical prostatectomy pad-test incontinence functional outcome |
| title | Correlation of Urine Loss after Catheter Removal and Early Continence in Men Undergoing Radical Prostatectomy |
| title_full | Correlation of Urine Loss after Catheter Removal and Early Continence in Men Undergoing Radical Prostatectomy |
| title_fullStr | Correlation of Urine Loss after Catheter Removal and Early Continence in Men Undergoing Radical Prostatectomy |
| title_full_unstemmed | Correlation of Urine Loss after Catheter Removal and Early Continence in Men Undergoing Radical Prostatectomy |
| title_short | Correlation of Urine Loss after Catheter Removal and Early Continence in Men Undergoing Radical Prostatectomy |
| title_sort | correlation of urine loss after catheter removal and early continence in men undergoing radical prostatectomy |
| topic | urinary incontinence radical prostatectomy pad-test incontinence functional outcome |
| url | https://www.mdpi.com/1718-7729/28/6/399 |
| work_keys_str_mv | AT benedikthoeh correlationofurinelossaftercatheterremovalandearlycontinenceinmenundergoingradicalprostatectomy AT felixpreisser correlationofurinelossaftercatheterremovalandearlycontinenceinmenundergoingradicalprostatectomy AT mikewenzel correlationofurinelossaftercatheterremovalandearlycontinenceinmenundergoingradicalprostatectomy AT clarahumke correlationofurinelossaftercatheterremovalandearlycontinenceinmenundergoingradicalprostatectomy AT clarissawittler correlationofurinelossaftercatheterremovalandearlycontinenceinmenundergoingradicalprostatectomy AT janlhohenhorst correlationofurinelossaftercatheterremovalandearlycontinenceinmenundergoingradicalprostatectomy AT majavolckmannwilde correlationofurinelossaftercatheterremovalandearlycontinenceinmenundergoingradicalprostatectomy AT jenskollermann correlationofurinelossaftercatheterremovalandearlycontinenceinmenundergoingradicalprostatectomy AT thomassteuber correlationofurinelossaftercatheterremovalandearlycontinenceinmenundergoingradicalprostatectomy AT markusgraefen correlationofurinelossaftercatheterremovalandearlycontinenceinmenundergoingradicalprostatectomy AT deryatilki correlationofurinelossaftercatheterremovalandearlycontinenceinmenundergoingradicalprostatectomy AT pierreikarakiewicz correlationofurinelossaftercatheterremovalandearlycontinenceinmenundergoingradicalprostatectomy AT andreasbecker correlationofurinelossaftercatheterremovalandearlycontinenceinmenundergoingradicalprostatectomy AT luisakluth correlationofurinelossaftercatheterremovalandearlycontinenceinmenundergoingradicalprostatectomy AT felixkhchun correlationofurinelossaftercatheterremovalandearlycontinenceinmenundergoingradicalprostatectomy AT philippmandel correlationofurinelossaftercatheterremovalandearlycontinenceinmenundergoingradicalprostatectomy |