Synergistic lipid compositions for albumin receptor mediated delivery of mRNA to the liver
Lipid-like nanoparticles have applications as non-viral delivery systems for mRNA. Here, the authors develop biodegradable lipids with improved clearance and reduced toxicity.
Main Authors: | Lei Miao, Jiaqi Lin, Yuxuan Huang, Linxian Li, Derfogail Delcassian, Yifan Ge, Yunhua Shi, Daniel G. Anderson |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2020-05-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-020-16248-y |
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