CUX1, A Controversial Player in Tumor Development

CUX1, A Controversial Player in Tumor Development

CUX1 belongs to the homeodomain transcription factor family and is evolutionarily and functionally conserved from Drosophila to humans. In addition to the involvement in various physiological events including tissue development, cell proliferation, differentiation and migration, and DNA damage respo...

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Bibliographic Details
Main Authors: Ning Liu, Qiliang Sun, Long Wan, Xuan Wang, Yu Feng, Judong Luo, Hailong Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Oncology
Subjects:
CUX1
haploinsufficient tumor suppressor
tumor progression
DNA damage
KRAS mutation
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00738/full

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