Iron deficiency anemia in a patient with hereditary hemorrhagic telangiectasia. Case report
RenduOslerWeber disease or hereditary hemorrhagic telangiectasia (HHT) is a rare autosomal dominant disease. It is characterized by vascular dysplasia with the formation of telangiectasias on the skin, mucous membranes of the respiratory and digestive tracts, arteriovenous malformations (AVMs) in th...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | Russian |
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"Consilium Medicum" Publishing house
2023-09-01
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| Series: | Терапевтический архив |
| Subjects: | |
| Online Access: | https://ter-arkhiv.ru/0040-3660/article/viewFile/595930/135404 |
| _version_ | 1797634640366796800 |
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| author | Maria A. Mozdon Rodion V. Ponomarev Nina V. Tsvetaeva Aleksey V. Shabrin Evgeniya I. Ermachenkova Sergei E. Larichev Elena A. Lukina |
| author_facet | Maria A. Mozdon Rodion V. Ponomarev Nina V. Tsvetaeva Aleksey V. Shabrin Evgeniya I. Ermachenkova Sergei E. Larichev Elena A. Lukina |
| author_sort | Maria A. Mozdon |
| collection | DOAJ |
| description | RenduOslerWeber disease or hereditary hemorrhagic telangiectasia (HHT) is a rare autosomal dominant disease. It is characterized by vascular dysplasia with the formation of telangiectasias on the skin, mucous membranes of the respiratory and digestive tracts, arteriovenous malformations (AVMs) in the internal organs, which is manifested by bleeding. Diagnosis is based on Curacao criteria: recurrent and spontaneous nosebleeds, multiple telangiectases on the characteristic localizations, AVMs in one or more of the internal organs, a family history of HHT (i.e. first-degree relative who meets these same criteria for definite HHT). Therapy is aimed at preventing and stopping gastrointestinal, nosebleeds, correction of iron deficiency anemia. A promising method of therapy is the use of angiogenesis inhibitors, in particular bevacizumab. The article presents a description of a clinical case of HHT in a 49-year-old woman with telangiectisia on the mucous membrane of the tongue, gastrointestinal tract and liver AVMs. |
| first_indexed | 2024-03-11T12:10:28Z |
| format | Article |
| id | doaj.art-27090d2f6f9a436b86f0f02c1fa3aced |
| institution | Directory Open Access Journal |
| issn | 0040-3660 2309-5342 |
| language | Russian |
| last_indexed | 2024-03-11T12:10:28Z |
| publishDate | 2023-09-01 |
| publisher | "Consilium Medicum" Publishing house |
| record_format | Article |
| series | Терапевтический архив |
| spelling | doaj.art-27090d2f6f9a436b86f0f02c1fa3aced2023-11-07T14:01:32Zrus"Consilium Medicum" Publishing houseТерапевтический архив0040-36602309-53422023-09-0195758058510.26442/00403660.2023.07.20230378324Iron deficiency anemia in a patient with hereditary hemorrhagic telangiectasia. Case reportMaria A. Mozdon0https://orcid.org/0009-0008-1358-6203Rodion V. Ponomarev1https://orcid.org/0000-0002-1218-0796Nina V. Tsvetaeva2https://orcid.org/0000-0002-0977-215XAleksey V. Shabrin3https://orcid.org/0000-0003-1901-6216Evgeniya I. Ermachenkova4https://orcid.org/0000-0003-1380-8423Sergei E. Larichev5https://orcid.org/0000-0003-1931-474XElena A. Lukina6https://orcid.org/0000-0002-8774-850XNational Medical Research Center for HematologyNational Medical Research Center for HematologyNational Medical Research Center for HematologyCity Clinical Hospital №17City Clinical Hospital №17City Clinical Hospital №17National Medical Research Center for HematologyRenduOslerWeber disease or hereditary hemorrhagic telangiectasia (HHT) is a rare autosomal dominant disease. It is characterized by vascular dysplasia with the formation of telangiectasias on the skin, mucous membranes of the respiratory and digestive tracts, arteriovenous malformations (AVMs) in the internal organs, which is manifested by bleeding. Diagnosis is based on Curacao criteria: recurrent and spontaneous nosebleeds, multiple telangiectases on the characteristic localizations, AVMs in one or more of the internal organs, a family history of HHT (i.e. first-degree relative who meets these same criteria for definite HHT). Therapy is aimed at preventing and stopping gastrointestinal, nosebleeds, correction of iron deficiency anemia. A promising method of therapy is the use of angiogenesis inhibitors, in particular bevacizumab. The article presents a description of a clinical case of HHT in a 49-year-old woman with telangiectisia on the mucous membrane of the tongue, gastrointestinal tract and liver AVMs.https://ter-arkhiv.ru/0040-3660/article/viewFile/595930/135404rendu–osler–weber diseasehereditary hemorrhagic telangiectasianosebleedsiron deficiency anemiaclinical case |
| spellingShingle | Maria A. Mozdon Rodion V. Ponomarev Nina V. Tsvetaeva Aleksey V. Shabrin Evgeniya I. Ermachenkova Sergei E. Larichev Elena A. Lukina Iron deficiency anemia in a patient with hereditary hemorrhagic telangiectasia. Case report Терапевтический архив rendu–osler–weber disease hereditary hemorrhagic telangiectasia nosebleeds iron deficiency anemia clinical case |
| title | Iron deficiency anemia in a patient with hereditary hemorrhagic telangiectasia. Case report |
| title_full | Iron deficiency anemia in a patient with hereditary hemorrhagic telangiectasia. Case report |
| title_fullStr | Iron deficiency anemia in a patient with hereditary hemorrhagic telangiectasia. Case report |
| title_full_unstemmed | Iron deficiency anemia in a patient with hereditary hemorrhagic telangiectasia. Case report |
| title_short | Iron deficiency anemia in a patient with hereditary hemorrhagic telangiectasia. Case report |
| title_sort | iron deficiency anemia in a patient with hereditary hemorrhagic telangiectasia case report |
| topic | rendu–osler–weber disease hereditary hemorrhagic telangiectasia nosebleeds iron deficiency anemia clinical case |
| url | https://ter-arkhiv.ru/0040-3660/article/viewFile/595930/135404 |
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