A novel antibacterial and fluorescent coating composed of polydopamine and carbon dots on the surface of orthodontic brackets
Abstract Many kinds of antibacterial coatings have been designed to prevent the adherence of bacteria onto the surface of a fixed orthodontic device of brackets. However, the problems such as weak binding force, undetectable, drug resistance, cytotoxicity and short duration needed to be solved. Thus...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer
2023-02-01
|
| Series: | Journal of Materials Science: Materials in Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s10856-023-06712-8 |
| _version_ | 1797865656924766208 |
|---|---|
| author | Yixi Wang Chuanyang Ding Zhangjie Ge Zhipeng Li Lixin Chen Xiaolong Guo Genxi Dong Ping Zhou |
| author_facet | Yixi Wang Chuanyang Ding Zhangjie Ge Zhipeng Li Lixin Chen Xiaolong Guo Genxi Dong Ping Zhou |
| author_sort | Yixi Wang |
| collection | DOAJ |
| description | Abstract Many kinds of antibacterial coatings have been designed to prevent the adherence of bacteria onto the surface of a fixed orthodontic device of brackets. However, the problems such as weak binding force, undetectable, drug resistance, cytotoxicity and short duration needed to be solved. Thus, it has great value in developing novel coating methods with long-term antibacterial and fluorescence properties according to the clinical application of brackets. In this study, we synthesized blue fluorescent carbon dots (HCDs) using the traditional Chinese medicinal honokiol, which could cause irreversible killing effects on both gram-positive and gram-negative bacteria through positive charges on the surface and inducing reactive oxygen species (ROS) production. Based on this, the surface of brackets was serially modified with polydopamine and HCDs, taking advantage of the strong adhesive properties as well as the negative surface charge of polydopamine particles. It is found that this coating exhibits stable antibacterial properties in 14 days with good biocompatibility, which can provide a new solution and strategy to solve the series of hazards caused by bacterial adhesion on the surface of orthodontic brackets. Graphical Abstract |
| first_indexed | 2024-04-09T23:11:39Z |
| format | Article |
| id | doaj.art-270fe51af1cf4a5f8ee487f396f648a6 |
| institution | Directory Open Access Journal |
| issn | 1573-4838 |
| language | English |
| last_indexed | 2024-04-09T23:11:39Z |
| publishDate | 2023-02-01 |
| publisher | Springer |
| record_format | Article |
| series | Journal of Materials Science: Materials in Medicine |
| spelling | doaj.art-270fe51af1cf4a5f8ee487f396f648a62023-03-22T10:18:38ZengSpringerJournal of Materials Science: Materials in Medicine1573-48382023-02-0134211210.1007/s10856-023-06712-8A novel antibacterial and fluorescent coating composed of polydopamine and carbon dots on the surface of orthodontic bracketsYixi Wang0Chuanyang Ding1Zhangjie Ge2Zhipeng Li3Lixin Chen4Xiaolong Guo5Genxi Dong6Ping Zhou7School and Hospital of Stomatology, Lanzhou University, No.222 Tianshui South RoadSchool and Hospital of Stomatology, Lanzhou University, No.222 Tianshui South RoadSchool and Hospital of Stomatology, Lanzhou University, No.222 Tianshui South RoadSchool and Hospital of Stomatology, Lanzhou University, No.222 Tianshui South RoadSchool and Hospital of Stomatology, Lanzhou University, No.222 Tianshui South RoadSchool and Hospital of Stomatology, Lanzhou University, No.222 Tianshui South RoadSchool and Hospital of Stomatology, Lanzhou University, No.222 Tianshui South RoadSchool and Hospital of Stomatology, Lanzhou University, No.222 Tianshui South RoadAbstract Many kinds of antibacterial coatings have been designed to prevent the adherence of bacteria onto the surface of a fixed orthodontic device of brackets. However, the problems such as weak binding force, undetectable, drug resistance, cytotoxicity and short duration needed to be solved. Thus, it has great value in developing novel coating methods with long-term antibacterial and fluorescence properties according to the clinical application of brackets. In this study, we synthesized blue fluorescent carbon dots (HCDs) using the traditional Chinese medicinal honokiol, which could cause irreversible killing effects on both gram-positive and gram-negative bacteria through positive charges on the surface and inducing reactive oxygen species (ROS) production. Based on this, the surface of brackets was serially modified with polydopamine and HCDs, taking advantage of the strong adhesive properties as well as the negative surface charge of polydopamine particles. It is found that this coating exhibits stable antibacterial properties in 14 days with good biocompatibility, which can provide a new solution and strategy to solve the series of hazards caused by bacterial adhesion on the surface of orthodontic brackets. Graphical Abstracthttps://doi.org/10.1007/s10856-023-06712-8Honokiol carbon dotsPolydopamineAntibacterial coatingBracketsReactive oxygen species |
| spellingShingle | Yixi Wang Chuanyang Ding Zhangjie Ge Zhipeng Li Lixin Chen Xiaolong Guo Genxi Dong Ping Zhou A novel antibacterial and fluorescent coating composed of polydopamine and carbon dots on the surface of orthodontic brackets Journal of Materials Science: Materials in Medicine Honokiol carbon dots Polydopamine Antibacterial coating Brackets Reactive oxygen species |
| title | A novel antibacterial and fluorescent coating composed of polydopamine and carbon dots on the surface of orthodontic brackets |
| title_full | A novel antibacterial and fluorescent coating composed of polydopamine and carbon dots on the surface of orthodontic brackets |
| title_fullStr | A novel antibacterial and fluorescent coating composed of polydopamine and carbon dots on the surface of orthodontic brackets |
| title_full_unstemmed | A novel antibacterial and fluorescent coating composed of polydopamine and carbon dots on the surface of orthodontic brackets |
| title_short | A novel antibacterial and fluorescent coating composed of polydopamine and carbon dots on the surface of orthodontic brackets |
| title_sort | novel antibacterial and fluorescent coating composed of polydopamine and carbon dots on the surface of orthodontic brackets |
| topic | Honokiol carbon dots Polydopamine Antibacterial coating Brackets Reactive oxygen species |
| url | https://doi.org/10.1007/s10856-023-06712-8 |
| work_keys_str_mv | AT yixiwang anovelantibacterialandfluorescentcoatingcomposedofpolydopamineandcarbondotsonthesurfaceoforthodonticbrackets AT chuanyangding anovelantibacterialandfluorescentcoatingcomposedofpolydopamineandcarbondotsonthesurfaceoforthodonticbrackets AT zhangjiege anovelantibacterialandfluorescentcoatingcomposedofpolydopamineandcarbondotsonthesurfaceoforthodonticbrackets AT zhipengli anovelantibacterialandfluorescentcoatingcomposedofpolydopamineandcarbondotsonthesurfaceoforthodonticbrackets AT lixinchen anovelantibacterialandfluorescentcoatingcomposedofpolydopamineandcarbondotsonthesurfaceoforthodonticbrackets AT xiaolongguo anovelantibacterialandfluorescentcoatingcomposedofpolydopamineandcarbondotsonthesurfaceoforthodonticbrackets AT genxidong anovelantibacterialandfluorescentcoatingcomposedofpolydopamineandcarbondotsonthesurfaceoforthodonticbrackets AT pingzhou anovelantibacterialandfluorescentcoatingcomposedofpolydopamineandcarbondotsonthesurfaceoforthodonticbrackets AT yixiwang novelantibacterialandfluorescentcoatingcomposedofpolydopamineandcarbondotsonthesurfaceoforthodonticbrackets AT chuanyangding novelantibacterialandfluorescentcoatingcomposedofpolydopamineandcarbondotsonthesurfaceoforthodonticbrackets AT zhangjiege novelantibacterialandfluorescentcoatingcomposedofpolydopamineandcarbondotsonthesurfaceoforthodonticbrackets AT zhipengli novelantibacterialandfluorescentcoatingcomposedofpolydopamineandcarbondotsonthesurfaceoforthodonticbrackets AT lixinchen novelantibacterialandfluorescentcoatingcomposedofpolydopamineandcarbondotsonthesurfaceoforthodonticbrackets AT xiaolongguo novelantibacterialandfluorescentcoatingcomposedofpolydopamineandcarbondotsonthesurfaceoforthodonticbrackets AT genxidong novelantibacterialandfluorescentcoatingcomposedofpolydopamineandcarbondotsonthesurfaceoforthodonticbrackets AT pingzhou novelantibacterialandfluorescentcoatingcomposedofpolydopamineandcarbondotsonthesurfaceoforthodonticbrackets |