Moderate–Vigorous Physical Activity and Clinical Outcomes in Adults with Nondialysis Chronic Kidney Disease
The health benefits of physical activity (PA) are well known. However, the association between an adequate amount of moderate–vigorous PA (MVPA) and clinical outcomes has limited evidence in chronic kidney disease (CKD). We assessed PA using a self-administered questionnaire. The amount of MVPA was...
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| Format: | Article |
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MDPI AG
2021-07-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/10/15/3365 |
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| author | Ji Hye Kim Young Youl Hyun Kyu-Beck Lee Sung Woo Lee Hayne Cho Park Wookyung Chung Joongyub Lee Yun Kyu Oh Kook-Hwan Oh Dong-Wan Chae Curie Ahn on behalf of the KoreaN Cohort Study for Outcome in Patients With CKD (KNOW-CKD) Study Group |
| author_facet | Ji Hye Kim Young Youl Hyun Kyu-Beck Lee Sung Woo Lee Hayne Cho Park Wookyung Chung Joongyub Lee Yun Kyu Oh Kook-Hwan Oh Dong-Wan Chae Curie Ahn on behalf of the KoreaN Cohort Study for Outcome in Patients With CKD (KNOW-CKD) Study Group |
| author_sort | Ji Hye Kim |
| collection | DOAJ |
| description | The health benefits of physical activity (PA) are well known. However, the association between an adequate amount of moderate–vigorous PA (MVPA) and clinical outcomes has limited evidence in chronic kidney disease (CKD). We assessed PA using a self-administered questionnaire. The amount of MVPA was categorized into four groups: none, low, moderate, and high (0, <7.5, 7.5–14.9, and 15.0–29.9 metabolic equivalent-hours/week, respectively). We analyzed the association between the amount of MVPA and clinical outcomes. Among a total of 1909 adults with CKD, adults with MVPA showed various beneficial outcomes compared to those with no MVPA in a Kaplan–Meier curve followed over a median of 5.9 years. In multivariable-adjusted Cox proportional hazard models, a low and a moderate amount of MVPA was associated with a lower risk of all-cause death. A moderate amount of MVPA was associated with a lower risk of cardiovascular events. A high amount of MVPA was associated with a lower risk of end-stage kidney disease in ESKD in 1324 adults with eGFR <60 mL/min/1.73 m<sup>2</sup>. Age and sex modified the relationships between MVPA and clinical outcomes. MVPA is associated with various beneficial outcomes across the amount of MVPA. PA plans should be tailored for individual adults with CKD. |
| first_indexed | 2024-03-10T09:12:45Z |
| format | Article |
| id | doaj.art-27138c6932644b2a99126c410c0b7c02 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T09:12:45Z |
| publishDate | 2021-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-27138c6932644b2a99126c410c0b7c022023-11-22T05:49:42ZengMDPI AGJournal of Clinical Medicine2077-03832021-07-011015336510.3390/jcm10153365Moderate–Vigorous Physical Activity and Clinical Outcomes in Adults with Nondialysis Chronic Kidney DiseaseJi Hye Kim0Young Youl Hyun1Kyu-Beck Lee2Sung Woo Lee3Hayne Cho Park4Wookyung Chung5Joongyub Lee6Yun Kyu Oh7Kook-Hwan Oh8Dong-Wan Chae9Curie Ahn10on behalf of the KoreaN Cohort Study for Outcome in Patients With CKD (KNOW-CKD) Study GroupDivision of Nephrology, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, 29 Saemunan-ro, Jongno-gu, Seoul 03181, KoreaDivision of Nephrology, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, 29 Saemunan-ro, Jongno-gu, Seoul 03181, KoreaDivision of Nephrology, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, 29 Saemunan-ro, Jongno-gu, Seoul 03181, KoreaEulji Medical Center, Department of Internal Medicine, Eulji University, Seoul 01830, KoreaDepartment of Internal Medicine, Kangnam Sacred Heart Hospital, Hallym University Medical Center, Seoul 07742, KoreaDepartment of Internal Medicine, Gil Hospital, Gachon University, Incheon 21565, KoreaDepartment of Prevention and Management, Inha University Hospital, Inha University School of Medicine, Incheon 22332, KoreaDepartment of Internal Medicine, Seoul National University Boramae Hospital, Seoul 07061, KoreaDepartment of Internal Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul 03080, KoreaDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam-si 13620, KoreaDepartment of Internal Medicine, National Medical Center, Seoul 04564, KoreaThe health benefits of physical activity (PA) are well known. However, the association between an adequate amount of moderate–vigorous PA (MVPA) and clinical outcomes has limited evidence in chronic kidney disease (CKD). We assessed PA using a self-administered questionnaire. The amount of MVPA was categorized into four groups: none, low, moderate, and high (0, <7.5, 7.5–14.9, and 15.0–29.9 metabolic equivalent-hours/week, respectively). We analyzed the association between the amount of MVPA and clinical outcomes. Among a total of 1909 adults with CKD, adults with MVPA showed various beneficial outcomes compared to those with no MVPA in a Kaplan–Meier curve followed over a median of 5.9 years. In multivariable-adjusted Cox proportional hazard models, a low and a moderate amount of MVPA was associated with a lower risk of all-cause death. A moderate amount of MVPA was associated with a lower risk of cardiovascular events. A high amount of MVPA was associated with a lower risk of end-stage kidney disease in ESKD in 1324 adults with eGFR <60 mL/min/1.73 m<sup>2</sup>. Age and sex modified the relationships between MVPA and clinical outcomes. MVPA is associated with various beneficial outcomes across the amount of MVPA. PA plans should be tailored for individual adults with CKD.https://www.mdpi.com/2077-0383/10/15/3365physical activityclinical outcomeschronic kidney disease |
| spellingShingle | Ji Hye Kim Young Youl Hyun Kyu-Beck Lee Sung Woo Lee Hayne Cho Park Wookyung Chung Joongyub Lee Yun Kyu Oh Kook-Hwan Oh Dong-Wan Chae Curie Ahn on behalf of the KoreaN Cohort Study for Outcome in Patients With CKD (KNOW-CKD) Study Group Moderate–Vigorous Physical Activity and Clinical Outcomes in Adults with Nondialysis Chronic Kidney Disease Journal of Clinical Medicine physical activity clinical outcomes chronic kidney disease |
| title | Moderate–Vigorous Physical Activity and Clinical Outcomes in Adults with Nondialysis Chronic Kidney Disease |
| title_full | Moderate–Vigorous Physical Activity and Clinical Outcomes in Adults with Nondialysis Chronic Kidney Disease |
| title_fullStr | Moderate–Vigorous Physical Activity and Clinical Outcomes in Adults with Nondialysis Chronic Kidney Disease |
| title_full_unstemmed | Moderate–Vigorous Physical Activity and Clinical Outcomes in Adults with Nondialysis Chronic Kidney Disease |
| title_short | Moderate–Vigorous Physical Activity and Clinical Outcomes in Adults with Nondialysis Chronic Kidney Disease |
| title_sort | moderate vigorous physical activity and clinical outcomes in adults with nondialysis chronic kidney disease |
| topic | physical activity clinical outcomes chronic kidney disease |
| url | https://www.mdpi.com/2077-0383/10/15/3365 |
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