In vitro fosfomycin activity in vancomycin-resistant Enterococcus faecalis
Enterococci are part of the endogenous flora of human beings, are naturally resistant to several classes of antimicrobials, and are able to acquire resistance with relative ease. Currently the vancomycin-resistant enterococci are spread all over the world and treatment options for infections caused...
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Format: | Article |
Language: | English |
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Elsevier
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Series: | Brazilian Journal of Infectious Diseases |
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Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702009000200010&lng=en&tlng=en |
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author | Silvana Superti Cícero Armídio Gomes Dias Pedro Alves d'Azevedo |
author_facet | Silvana Superti Cícero Armídio Gomes Dias Pedro Alves d'Azevedo |
author_sort | Silvana Superti |
collection | DOAJ |
description | Enterococci are part of the endogenous flora of human beings, are naturally resistant to several classes of antimicrobials, and are able to acquire resistance with relative ease. Currently the vancomycin-resistant enterococci are spread all over the world and treatment options for infections caused by it are often extremely limited. We assessed 193 vancomycin-resistant Enterococcus faecalis isolates collected from four different hospitals in Porto Alegre for their susceptibility to fosfomycin using the E-test and agar diffusion. Fosfomycin proved to be active in vitro against the great majority of isolates, indicating that it is a valid option in the treatment of these infections. |
first_indexed | 2024-12-20T20:51:27Z |
format | Article |
id | doaj.art-2715ae762ee54fd3b49d2ec3f84eb8bd |
institution | Directory Open Access Journal |
issn | 1678-4391 |
language | English |
last_indexed | 2024-12-20T20:51:27Z |
publisher | Elsevier |
record_format | Article |
series | Brazilian Journal of Infectious Diseases |
spelling | doaj.art-2715ae762ee54fd3b49d2ec3f84eb8bd2022-12-21T19:26:54ZengElsevierBrazilian Journal of Infectious Diseases1678-439113212312410.1590/S1413-86702009000200010S1413-86702009000200010In vitro fosfomycin activity in vancomycin-resistant Enterococcus faecalisSilvana Superti0Cícero Armídio Gomes Dias1Pedro Alves d'Azevedo2Universidade Federal de Ciências da Saúde de Porto AlegreUniversidade Federal de Ciências da Saúde de Porto AlegreUniversidade Federal de Ciências da Saúde de Porto AlegreEnterococci are part of the endogenous flora of human beings, are naturally resistant to several classes of antimicrobials, and are able to acquire resistance with relative ease. Currently the vancomycin-resistant enterococci are spread all over the world and treatment options for infections caused by it are often extremely limited. We assessed 193 vancomycin-resistant Enterococcus faecalis isolates collected from four different hospitals in Porto Alegre for their susceptibility to fosfomycin using the E-test and agar diffusion. Fosfomycin proved to be active in vitro against the great majority of isolates, indicating that it is a valid option in the treatment of these infections.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702009000200010&lng=en&tlng=enEnterococcus faecalisvancomycin-resistanceVREfosfomycin |
spellingShingle | Silvana Superti Cícero Armídio Gomes Dias Pedro Alves d'Azevedo In vitro fosfomycin activity in vancomycin-resistant Enterococcus faecalis Brazilian Journal of Infectious Diseases Enterococcus faecalis vancomycin-resistance VRE fosfomycin |
title | In vitro fosfomycin activity in vancomycin-resistant Enterococcus faecalis |
title_full | In vitro fosfomycin activity in vancomycin-resistant Enterococcus faecalis |
title_fullStr | In vitro fosfomycin activity in vancomycin-resistant Enterococcus faecalis |
title_full_unstemmed | In vitro fosfomycin activity in vancomycin-resistant Enterococcus faecalis |
title_short | In vitro fosfomycin activity in vancomycin-resistant Enterococcus faecalis |
title_sort | in vitro fosfomycin activity in vancomycin resistant enterococcus faecalis |
topic | Enterococcus faecalis vancomycin-resistance VRE fosfomycin |
url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702009000200010&lng=en&tlng=en |
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