Reaching for the Holy Grail: insights from infection/cure models on the prospects for vaccines for Trypanosoma cruzi infection

Reaching for the Holy Grail: insights from infection/cure models on the prospects for vaccines for Trypanosoma cruzi infection

Prevention of Trypanosoma cruzi infection in mammals likely depends on either prevention of the invading trypomastigotes from infecting host cells or the rapid recognition and killing of the newly infected cells by T. cruzi-specific T cells. We show here that multiple rounds of infection and cure (b...

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Bibliographic Details
Main Authors: Juan Bustamante, Rick Tarleton
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2015-05-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
Chagas disease
vaccine
Trypanosoma cruzi
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762015000300445&lng=en&tlng=en

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