Total Lymfosit Count (TLC) with CD4 in HIV/AIDS Patients at Kupang

Human Immunodeficiency Virus (HIV) is a retrovirus originating from the retroviridae family of the genus lentivirus that infects and damages cells that have a molecule Cluster of Differentiation 4 (CD4), especially T lymphocytes that have receptors with high affinity for HIV. Total lymphocyte count...

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Main Authors: Adrianus Ola Wuan, Ayorince Herlinalt Gloria Banunu, Norma Tiku Kambuno
Format: Article
Language:Indonesian
Published: Poltekkes Kemenkes Yogyakarta 2019-09-01
Series:Jurnal Teknologi Laboratorium
Subjects:
Online Access:https://www.teknolabjournal.com/index.php/Jtl/article/view/189
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author Adrianus Ola Wuan
Ayorince Herlinalt Gloria Banunu
Norma Tiku Kambuno
author_facet Adrianus Ola Wuan
Ayorince Herlinalt Gloria Banunu
Norma Tiku Kambuno
author_sort Adrianus Ola Wuan
collection DOAJ
description Human Immunodeficiency Virus (HIV) is a retrovirus originating from the retroviridae family of the genus lentivirus that infects and damages cells that have a molecule Cluster of Differentiation 4 (CD4), especially T lymphocytes that have receptors with high affinity for HIV. Total lymphocyte count / TLC has been proposed as an alternative guide to CD4 in limited health facilities. This study aims to determine the correlation between Total Lymphocyte Count (TLC) and CD4 in HIV/AIDS patients in the W.Z. Johannes Kupang hospital. The type of this research was observational analytic with a cross-sectional design. The study was conducted on 121 samples of patients who performed CD4 examination and Total Lymphocytic Count (TLC) in the laboratory of W.Z.Johannes Kupang Hospital. The Spearman correlation test shows a significance value of 0,000 with a Spearman correlation value of 0.799. Based on the results of this study it can be concluded that there is a significant correlation between Total Lymphocyte Count and CD4 and shows the direction of positive correlation with a very strong relationship, where the increase in the number of Total Lymphocyte Count is in line with the increase in CD4 counts.
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spelling doaj.art-271cc45239bc4093ab17f4e2a32d73a82022-12-21T23:53:33ZindPoltekkes Kemenkes YogyakartaJurnal Teknologi Laboratorium2338-56342580-01912019-09-0182707510.29238/teknolabjournal.v8i2.189189Total Lymfosit Count (TLC) with CD4 in HIV/AIDS Patients at KupangAdrianus Ola Wuan0Ayorince Herlinalt Gloria Banunu1Norma Tiku Kambuno2Department of Medical Laboratory Technology, Poltekkes Kemenkes Kupang, IndonesiaLaboratory of Clinical Pathology, RSUD. W.Z. Johannes, Kupang, IndonesiaDepartment of Medical Laboratory Technology, Poltekkes Kemenkes Kupang, IndonesiaHuman Immunodeficiency Virus (HIV) is a retrovirus originating from the retroviridae family of the genus lentivirus that infects and damages cells that have a molecule Cluster of Differentiation 4 (CD4), especially T lymphocytes that have receptors with high affinity for HIV. Total lymphocyte count / TLC has been proposed as an alternative guide to CD4 in limited health facilities. This study aims to determine the correlation between Total Lymphocyte Count (TLC) and CD4 in HIV/AIDS patients in the W.Z. Johannes Kupang hospital. The type of this research was observational analytic with a cross-sectional design. The study was conducted on 121 samples of patients who performed CD4 examination and Total Lymphocytic Count (TLC) in the laboratory of W.Z.Johannes Kupang Hospital. The Spearman correlation test shows a significance value of 0,000 with a Spearman correlation value of 0.799. Based on the results of this study it can be concluded that there is a significant correlation between Total Lymphocyte Count and CD4 and shows the direction of positive correlation with a very strong relationship, where the increase in the number of Total Lymphocyte Count is in line with the increase in CD4 counts.https://www.teknolabjournal.com/index.php/Jtl/article/view/189cd4 count, total lymphocyte count, hiv / aids patients
spellingShingle Adrianus Ola Wuan
Ayorince Herlinalt Gloria Banunu
Norma Tiku Kambuno
Total Lymfosit Count (TLC) with CD4 in HIV/AIDS Patients at Kupang
Jurnal Teknologi Laboratorium
cd4 count, total lymphocyte count, hiv / aids patients
title Total Lymfosit Count (TLC) with CD4 in HIV/AIDS Patients at Kupang
title_full Total Lymfosit Count (TLC) with CD4 in HIV/AIDS Patients at Kupang
title_fullStr Total Lymfosit Count (TLC) with CD4 in HIV/AIDS Patients at Kupang
title_full_unstemmed Total Lymfosit Count (TLC) with CD4 in HIV/AIDS Patients at Kupang
title_short Total Lymfosit Count (TLC) with CD4 in HIV/AIDS Patients at Kupang
title_sort total lymfosit count tlc with cd4 in hiv aids patients at kupang
topic cd4 count, total lymphocyte count, hiv / aids patients
url https://www.teknolabjournal.com/index.php/Jtl/article/view/189
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