High-frequency multimodal training with a focus on Tai Chi in people with Parkinson’s disease: a pilot study
Background and objectivesCognitive decline is an important and common complication in patients with Parkinson’s disease (PD) since it significantly reduces the quality of life. A breakthrough in treating and preventing cognitive decline in PD remains to be achieved. This study aimed to evaluate the...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-02-01
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| Series: | Frontiers in Aging Neuroscience |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnagi.2024.1335951/full |
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| author | Ketevan Toloraia Ketevan Toloraia Ute Gschwandtner Ute Gschwandtner Peter Fuhr Peter Fuhr |
| author_facet | Ketevan Toloraia Ketevan Toloraia Ute Gschwandtner Ute Gschwandtner Peter Fuhr Peter Fuhr |
| author_sort | Ketevan Toloraia |
| collection | DOAJ |
| description | Background and objectivesCognitive decline is an important and common complication in patients with Parkinson’s disease (PD) since it significantly reduces the quality of life. A breakthrough in treating and preventing cognitive decline in PD remains to be achieved. This study aimed to evaluate the effectiveness of high-frequency and intensive multimodal training in improving motor and cognitive function.MethodsTwenty-eight patients diagnosed with idiopathic PD completed a comprehensive neuropsychological test battery and were neurologically examined. The patients of the intervention group (n = 15) underwent 2 weekly sessions of Tai Chi therapy over 4 weeks and participated in an individually tailored training program consisting of two modules (smartphone-based speech training and cognitive training). A matched control group consisted of n = 13 patients with PD who received computer-assisted cognitive training. The data were analyzed with repeated-measures ANOVA.ResultsFour weeks of high-frequency training showed significant effects on verbal and figural episodic memory and visuospatial function in the intervention group.Compared to the control group, the cognitive performance of the intervention group improved significantly in visuospatial function and figural episodic memory. A significant improvement was also shown in the intervention group in the Tinetti Mobility Test and the Epworth Sleepiness Scale. The significant effects in the Tinetti mobility test remained after the 6 months follow-up. After the intervention, the patients reported high motivation and satisfaction with the multimodal training.ConclusionIn patients with PD, a multimodal training program not only improves gait and stability but may also contribute to improving cognition.Clinical trial registrationClinicalTrials.gov Identifier: NCT04103255; https://register.clinicaltrials.gov/prs/app/action/LoginUser?ts=1&cx=-jg9qo4. |
| first_indexed | 2024-03-08T00:50:42Z |
| format | Article |
| id | doaj.art-271e6558e49240cf8c8e9dd5e2f5af54 |
| institution | Directory Open Access Journal |
| issn | 1663-4365 |
| language | English |
| last_indexed | 2024-03-08T00:50:42Z |
| publishDate | 2024-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Aging Neuroscience |
| spelling | doaj.art-271e6558e49240cf8c8e9dd5e2f5af542024-02-15T04:48:41ZengFrontiers Media S.A.Frontiers in Aging Neuroscience1663-43652024-02-011610.3389/fnagi.2024.13359511335951High-frequency multimodal training with a focus on Tai Chi in people with Parkinson’s disease: a pilot studyKetevan Toloraia0Ketevan Toloraia1Ute Gschwandtner2Ute Gschwandtner3Peter Fuhr4Peter Fuhr5Department of Clinical Research and Neurology, University Hospital Basel, Basel, SwitzerlandDepartment of Neurology, University Hospital Basel, Basel, SwitzerlandDepartment of Clinical Research and Neurology, University Hospital Basel, Basel, SwitzerlandDepartment of Neurology, University Hospital Basel, Basel, SwitzerlandDepartment of Clinical Research and Neurology, University Hospital Basel, Basel, SwitzerlandDepartment of Neurology, University Hospital Basel, Basel, SwitzerlandBackground and objectivesCognitive decline is an important and common complication in patients with Parkinson’s disease (PD) since it significantly reduces the quality of life. A breakthrough in treating and preventing cognitive decline in PD remains to be achieved. This study aimed to evaluate the effectiveness of high-frequency and intensive multimodal training in improving motor and cognitive function.MethodsTwenty-eight patients diagnosed with idiopathic PD completed a comprehensive neuropsychological test battery and were neurologically examined. The patients of the intervention group (n = 15) underwent 2 weekly sessions of Tai Chi therapy over 4 weeks and participated in an individually tailored training program consisting of two modules (smartphone-based speech training and cognitive training). A matched control group consisted of n = 13 patients with PD who received computer-assisted cognitive training. The data were analyzed with repeated-measures ANOVA.ResultsFour weeks of high-frequency training showed significant effects on verbal and figural episodic memory and visuospatial function in the intervention group.Compared to the control group, the cognitive performance of the intervention group improved significantly in visuospatial function and figural episodic memory. A significant improvement was also shown in the intervention group in the Tinetti Mobility Test and the Epworth Sleepiness Scale. The significant effects in the Tinetti mobility test remained after the 6 months follow-up. After the intervention, the patients reported high motivation and satisfaction with the multimodal training.ConclusionIn patients with PD, a multimodal training program not only improves gait and stability but may also contribute to improving cognition.Clinical trial registrationClinicalTrials.gov Identifier: NCT04103255; https://register.clinicaltrials.gov/prs/app/action/LoginUser?ts=1&cx=-jg9qo4.https://www.frontiersin.org/articles/10.3389/fnagi.2024.1335951/fullParkinson’s diseaseTai Chicognitive declinecognitioncognitive trainingmotor skills |
| spellingShingle | Ketevan Toloraia Ketevan Toloraia Ute Gschwandtner Ute Gschwandtner Peter Fuhr Peter Fuhr High-frequency multimodal training with a focus on Tai Chi in people with Parkinson’s disease: a pilot study Frontiers in Aging Neuroscience Parkinson’s disease Tai Chi cognitive decline cognition cognitive training motor skills |
| title | High-frequency multimodal training with a focus on Tai Chi in people with Parkinson’s disease: a pilot study |
| title_full | High-frequency multimodal training with a focus on Tai Chi in people with Parkinson’s disease: a pilot study |
| title_fullStr | High-frequency multimodal training with a focus on Tai Chi in people with Parkinson’s disease: a pilot study |
| title_full_unstemmed | High-frequency multimodal training with a focus on Tai Chi in people with Parkinson’s disease: a pilot study |
| title_short | High-frequency multimodal training with a focus on Tai Chi in people with Parkinson’s disease: a pilot study |
| title_sort | high frequency multimodal training with a focus on tai chi in people with parkinson s disease a pilot study |
| topic | Parkinson’s disease Tai Chi cognitive decline cognition cognitive training motor skills |
| url | https://www.frontiersin.org/articles/10.3389/fnagi.2024.1335951/full |
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