Decreased miR-497-5p Suppresses IL-6 Induced Atrophy in Muscle Cells

Decreased miR-497-5p Suppresses IL-6 Induced Atrophy in Muscle Cells

Interleukin-6 (IL-6) is a pro-inflammatory cytokine associated with skeletal muscle wasting in cancer cachexia. The control of gene expression by microRNAs (miRNAs) in muscle wasting involves the regulation of thousands of target transcripts. However, the miRNA-target networks associated with IL6-in...

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Bibliographic Details
Main Authors: Paula P. Freire, Sarah S. Cury, Letícia O. Lopes, Geysson J. Fernandez, Jianming Liu, Leonardo Nazario de Moraes, Grasieli de Oliveira, Jakeline S. Oliveira, Diogo de Moraes, Otavio Cabral-Marques, Maeli Dal-Pai-Silva, Xiaoyun Hu, Da-Zhi Wang, Robson F. Carvalho
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cells
Subjects:
Interleukin-6
muscle wasting
microRNAs
inflammation
Online Access:https://www.mdpi.com/2073-4409/10/12/3527

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