CARD9 deficiency improves the recovery of limb ischemia in mice with ambient fine particulate matter exposure

CARD9 deficiency improves the recovery of limb ischemia in mice with ambient fine particulate matter exposure

BackgroundExposure to fine particulate matter (PM) is a significant risk for cardiovascular diseases largely due to increased reactive oxygen species (ROS) production and inflammation. Caspase recruitment domain (CARD)9 is critically involved in innate immunity and inflammation. The present study wa...

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Bibliographic Details
Main Authors: Qiang Zhu, Xuanyou Liu, Hao Wu, Chunlin Yang, Meifang Wang, Feng Chen, Yuqi Cui, Hong Hao, Michael A. Hill, Zhenguo Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
PM exposure
ischemic limb
ROS
oxidative stress
macrophages
CARD9
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2023.1125717/full

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