A Lipidomics- and Transcriptomics-Based Analysis of the Intestine of Genetically Obese (<i>ob/ob</i>) and Diabetic (<i>db/db</i>) Mice: Links with Inflammation and Gut Microbiota

A Lipidomics- and Transcriptomics-Based Analysis of the Intestine of Genetically Obese (<i>ob/ob</i>) and Diabetic (<i>db/db</i>) Mice: Links with Inflammation and Gut Microbiota

Obesity is associated with a cluster of metabolic disorders, chronic low-grade inflammation, altered gut microbiota, increased intestinal permeability, and alterations of the lipid mediators of the expanded endocannabinoid (eCB) signaling system, or endocannabinoidome (eCBome). In the present study,...

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Bibliographic Details
Main Authors: Francesco Suriano, Claudia Manca, Nicolas Flamand, Matthias Van Hul, Nathalie M. Delzenne, Cristoforo Silvestri, Patrice D. Cani, Vincenzo Di Marzo
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Cells
Subjects:
lipidomics
transcriptomics
endocannabinoids
enzymes
intestine
obesity
Online Access:https://www.mdpi.com/2073-4409/12/3/411

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