Convalescent (Immune) Plasma Followed by Intravenous Immunoglobulin Infusion in an Adolescent with Severe COVID-19

Coronavirus disease 2019 (COVID-19) pandemic has drawn attention over old immunotherapeutic agents such as convalescent (immune) plasma (CIP). Here, an adolescent with severe COVID-19 case requiring CIP and intravenous immunoglobulin (IVIG) treatments is described. A 17-year-old male patient was bro...

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Main Authors: Öner Özdemir, Bahri Elmas, Hüseyin Sütlüoğlu, Mehmet Cemal Dönmez
Format: Article
Language:English
Published: Duzce University 2021-08-01
Series:Düzce Tıp Fakültesi Dergisi
Subjects:
Online Access:https://dergipark.org.tr/tr/download/article-file/1772177
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author Öner Özdemir
Bahri Elmas
Hüseyin Sütlüoğlu
Mehmet Cemal Dönmez
author_facet Öner Özdemir
Bahri Elmas
Hüseyin Sütlüoğlu
Mehmet Cemal Dönmez
author_sort Öner Özdemir
collection DOAJ
description Coronavirus disease 2019 (COVID-19) pandemic has drawn attention over old immunotherapeutic agents such as convalescent (immune) plasma (CIP). Here, an adolescent with severe COVID-19 case requiring CIP and intravenous immunoglobulin (IVIG) treatments is described. A 17-year-old male patient was brought to the emergency room with complaints of fever, fatigue, and severe cough. Two doses of CIP were infused to the patient because of the increase in persisting fever, dyspnea, and acute phase reactant levels after the third day of routine protocol treatment. IVIG therapy was begun for 2 days at a dose of 1 g/kg/day due to resurgence in acute phase reactants and progressing radiological findings following CIP transfusion. Our patient avoided mechanical ventilation and showed immediate clinical and radiological improvement with CIP transfusion followed by IVIG therapy. Timely initiation of CIP treatment followed by IVIG prevented the disease from worsening and helped to reduce the requirement for mechanical ventilation.
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spelling doaj.art-272a2ebfd54f40a1940a30e3839c634e2023-10-02T06:47:56ZengDuzce UniversityDüzce Tıp Fakültesi Dergisi1307-671X2021-08-0123222122410.18678/dtfd.93826997Convalescent (Immune) Plasma Followed by Intravenous Immunoglobulin Infusion in an Adolescent with Severe COVID-19Öner Özdemir0Bahri Elmas1Hüseyin Sütlüoğlu2Mehmet Cemal Dönmez3SAKARYA UNIVERSITYSAKARYA UNIVERSITYSAKARYA UNIVERSITYSAKARYA UNIVERSITYCoronavirus disease 2019 (COVID-19) pandemic has drawn attention over old immunotherapeutic agents such as convalescent (immune) plasma (CIP). Here, an adolescent with severe COVID-19 case requiring CIP and intravenous immunoglobulin (IVIG) treatments is described. A 17-year-old male patient was brought to the emergency room with complaints of fever, fatigue, and severe cough. Two doses of CIP were infused to the patient because of the increase in persisting fever, dyspnea, and acute phase reactant levels after the third day of routine protocol treatment. IVIG therapy was begun for 2 days at a dose of 1 g/kg/day due to resurgence in acute phase reactants and progressing radiological findings following CIP transfusion. Our patient avoided mechanical ventilation and showed immediate clinical and radiological improvement with CIP transfusion followed by IVIG therapy. Timely initiation of CIP treatment followed by IVIG prevented the disease from worsening and helped to reduce the requirement for mechanical ventilation.https://dergipark.org.tr/tr/download/article-file/1772177covid-19convalescent (immune) plasmaintravenous immunoglobulincovid-19intravenöz immunoglobulinkonvalesan (immün) plazma
spellingShingle Öner Özdemir
Bahri Elmas
Hüseyin Sütlüoğlu
Mehmet Cemal Dönmez
Convalescent (Immune) Plasma Followed by Intravenous Immunoglobulin Infusion in an Adolescent with Severe COVID-19
Düzce Tıp Fakültesi Dergisi
covid-19
convalescent (immune) plasma
intravenous immunoglobulin
covid-19
intravenöz immunoglobulin
konvalesan (immün) plazma
title Convalescent (Immune) Plasma Followed by Intravenous Immunoglobulin Infusion in an Adolescent with Severe COVID-19
title_full Convalescent (Immune) Plasma Followed by Intravenous Immunoglobulin Infusion in an Adolescent with Severe COVID-19
title_fullStr Convalescent (Immune) Plasma Followed by Intravenous Immunoglobulin Infusion in an Adolescent with Severe COVID-19
title_full_unstemmed Convalescent (Immune) Plasma Followed by Intravenous Immunoglobulin Infusion in an Adolescent with Severe COVID-19
title_short Convalescent (Immune) Plasma Followed by Intravenous Immunoglobulin Infusion in an Adolescent with Severe COVID-19
title_sort convalescent immune plasma followed by intravenous immunoglobulin infusion in an adolescent with severe covid 19
topic covid-19
convalescent (immune) plasma
intravenous immunoglobulin
covid-19
intravenöz immunoglobulin
konvalesan (immün) plazma
url https://dergipark.org.tr/tr/download/article-file/1772177
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AT bahrielmas convalescentimmuneplasmafollowedbyintravenousimmunoglobulininfusioninanadolescentwithseverecovid19
AT huseyinsutluoglu convalescentimmuneplasmafollowedbyintravenousimmunoglobulininfusioninanadolescentwithseverecovid19
AT mehmetcemaldonmez convalescentimmuneplasmafollowedbyintravenousimmunoglobulininfusioninanadolescentwithseverecovid19