The Agr Quorum Sensing System Represses Persister Formation through Regulation of Phenol Soluble Modulins in Staphylococcus aureus

The Agr Quorum Sensing System Represses Persister Formation through Regulation of Phenol Soluble Modulins in Staphylococcus aureus

The opportunistic pathogen Staphylococcus aureus has become an increasing threat to public health. While the Agr quorum sensing (QS) system is a master regulator of S. aureus virulence, its dysfunction has been frequently reported to promote bacteremia and mortality in clinical infections. Here we s...

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Bibliographic Details
Main Authors: Tao Xu, Xu-Yang Wang, Peng Cui, Yu-Meng Zhang, Wen-Hong Zhang, Ying Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Microbiology
Subjects:
Staphylococcus aureus
Agr
antibiotic
persister formation
sialic metabolism
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.02189/full

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