An Outbreak of Human Systemic Anthrax, including One Case of Anthrax Meningitis, Occurred in Calabria Region (Italy): A Description of a Successful One Health Approach
In this report, three cases of human cutaneous anthrax are described, one complicated by meningitis, and all were linked to a single infected bullock. A 41-year-old male truck driver, along with two male slaughterhouse workers, 45 and 42, were hospitalized for necrotic lesions of the arm associated...
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MDPI AG
2022-06-01
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| Series: | Life |
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| Online Access: | https://www.mdpi.com/2075-1729/12/6/909 |
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| author | Maurizio Guastalegname Valeria Rondinone Giuseppe Lucifora Alfredo Vallone Laura D’Argenio Giovanni Petracca Antonia Giordano Luigina Serrecchia Viviana Manzulli Lorenzo Pace Antonio Fasanella Domenico Simone Dora Cipolletta Domenico Galante |
| author_facet | Maurizio Guastalegname Valeria Rondinone Giuseppe Lucifora Alfredo Vallone Laura D’Argenio Giovanni Petracca Antonia Giordano Luigina Serrecchia Viviana Manzulli Lorenzo Pace Antonio Fasanella Domenico Simone Dora Cipolletta Domenico Galante |
| author_sort | Maurizio Guastalegname |
| collection | DOAJ |
| description | In this report, three cases of human cutaneous anthrax are described, one complicated by meningitis, and all were linked to a single infected bullock. A 41-year-old male truck driver, along with two male slaughterhouse workers, 45 and 42, were hospitalized for necrotic lesions of the arm associated with edema of the limb and high fever. All three patients were involved in transporting a bullock to the slaughterhouse. Microbiological examination on the prescapular lymph node and a piece of muscle from the bullock carcass showed the presence of <i>Bacillus anthracis</i>. The three patients underwent a biopsy of the affected tissues, and all samples tested positive for <i>B. anthracis</i> DNA using PCR. Furthermore, the truck driver also complained of an intense headache, and a CSF sampling was performed, showing him positive for <i>B. anthracis</i> by PCR, confirming the presumptive diagnosis of meningitis. Fast diagnosis and appropriate treatment are crucial for the management of human anthrax. Cooperation between human and veterinary medicine proved successful in diagnosing and resolving three human anthrax cases, confirming the reliability of the One Health approach for the surveillance of zoonoses. |
| first_indexed | 2024-03-09T23:14:24Z |
| format | Article |
| id | doaj.art-27374f56c224481fbbe4477ff393d1aa |
| institution | Directory Open Access Journal |
| issn | 2075-1729 |
| language | English |
| last_indexed | 2024-03-09T23:14:24Z |
| publishDate | 2022-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Life |
| spelling | doaj.art-27374f56c224481fbbe4477ff393d1aa2023-11-23T17:37:36ZengMDPI AGLife2075-17292022-06-0112690910.3390/life12060909An Outbreak of Human Systemic Anthrax, including One Case of Anthrax Meningitis, Occurred in Calabria Region (Italy): A Description of a Successful One Health ApproachMaurizio Guastalegname0Valeria Rondinone1Giuseppe Lucifora2Alfredo Vallone3Laura D’Argenio4Giovanni Petracca5Antonia Giordano6Luigina Serrecchia7Viviana Manzulli8Lorenzo Pace9Antonio Fasanella10Domenico Simone11Dora Cipolletta12Domenico Galante13Infectious Diseases Unit, Jazzolino Hospital, 89900 Vibo Valentia, ItalyIstituto Zooprofilattico Sperimentale della Puglia e della Basilicata, 71121 Foggia, ItalyIstituto Zooprofilattico Sperimentale del Mezzogiorno, 80055 Portici, ItalyInfectious Diseases Unit, Jazzolino Hospital, 89900 Vibo Valentia, ItalyInfectious Diseases Unit, Jazzolino Hospital, 89900 Vibo Valentia, ItalySurgery Unit, Jazzolino Hospital, 89900 Vibo Valentia, ItalyDepartment of Prevention, Azienda Sanitaria Provinciale Vibo Valentia, 89900 Vibo Valentia, ItalyIstituto Zooprofilattico Sperimentale della Puglia e della Basilicata, 71121 Foggia, ItalyIstituto Zooprofilattico Sperimentale della Puglia e della Basilicata, 71121 Foggia, ItalyIstituto Zooprofilattico Sperimentale della Puglia e della Basilicata, 71121 Foggia, ItalyIstituto Zooprofilattico Sperimentale della Puglia e della Basilicata, 71121 Foggia, ItalyIstituto Zooprofilattico Sperimentale della Puglia e della Basilicata, 71121 Foggia, ItalyIstituto Zooprofilattico Sperimentale della Puglia e della Basilicata, 71121 Foggia, ItalyIstituto Zooprofilattico Sperimentale della Puglia e della Basilicata, 71121 Foggia, ItalyIn this report, three cases of human cutaneous anthrax are described, one complicated by meningitis, and all were linked to a single infected bullock. A 41-year-old male truck driver, along with two male slaughterhouse workers, 45 and 42, were hospitalized for necrotic lesions of the arm associated with edema of the limb and high fever. All three patients were involved in transporting a bullock to the slaughterhouse. Microbiological examination on the prescapular lymph node and a piece of muscle from the bullock carcass showed the presence of <i>Bacillus anthracis</i>. The three patients underwent a biopsy of the affected tissues, and all samples tested positive for <i>B. anthracis</i> DNA using PCR. Furthermore, the truck driver also complained of an intense headache, and a CSF sampling was performed, showing him positive for <i>B. anthracis</i> by PCR, confirming the presumptive diagnosis of meningitis. Fast diagnosis and appropriate treatment are crucial for the management of human anthrax. Cooperation between human and veterinary medicine proved successful in diagnosing and resolving three human anthrax cases, confirming the reliability of the One Health approach for the surveillance of zoonoses.https://www.mdpi.com/2075-1729/12/6/909<i>Bacillus anthracis</i>One Healthcutaneous anthraxmeningitisantibiotic treatmentepidemiology |
| spellingShingle | Maurizio Guastalegname Valeria Rondinone Giuseppe Lucifora Alfredo Vallone Laura D’Argenio Giovanni Petracca Antonia Giordano Luigina Serrecchia Viviana Manzulli Lorenzo Pace Antonio Fasanella Domenico Simone Dora Cipolletta Domenico Galante An Outbreak of Human Systemic Anthrax, including One Case of Anthrax Meningitis, Occurred in Calabria Region (Italy): A Description of a Successful One Health Approach Life <i>Bacillus anthracis</i> One Health cutaneous anthrax meningitis antibiotic treatment epidemiology |
| title | An Outbreak of Human Systemic Anthrax, including One Case of Anthrax Meningitis, Occurred in Calabria Region (Italy): A Description of a Successful One Health Approach |
| title_full | An Outbreak of Human Systemic Anthrax, including One Case of Anthrax Meningitis, Occurred in Calabria Region (Italy): A Description of a Successful One Health Approach |
| title_fullStr | An Outbreak of Human Systemic Anthrax, including One Case of Anthrax Meningitis, Occurred in Calabria Region (Italy): A Description of a Successful One Health Approach |
| title_full_unstemmed | An Outbreak of Human Systemic Anthrax, including One Case of Anthrax Meningitis, Occurred in Calabria Region (Italy): A Description of a Successful One Health Approach |
| title_short | An Outbreak of Human Systemic Anthrax, including One Case of Anthrax Meningitis, Occurred in Calabria Region (Italy): A Description of a Successful One Health Approach |
| title_sort | outbreak of human systemic anthrax including one case of anthrax meningitis occurred in calabria region italy a description of a successful one health approach |
| topic | <i>Bacillus anthracis</i> One Health cutaneous anthrax meningitis antibiotic treatment epidemiology |
| url | https://www.mdpi.com/2075-1729/12/6/909 |
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