Emergence of the primordial pre-60S from the 90S pre-ribosome

Summary: Synthesis of ribosomes begins in the nucleolus with formation of the 90S pre-ribosome, during which the pre-40S and pre-60S pathways diverge by pre-rRNA cleavage. However, it remains unclear how, after this uncoupling, the earliest pre-60S subunit continues to develop. Here, we reveal a lar...

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Bibliographic Details
Main Authors: Sherif Ismail, Dirk Flemming, Matthias Thoms, José Vicente Gomes-Filho, Lennart Randau, Roland Beckmann, Ed Hurt
Format: Article
Language:English
Published: Elsevier 2022-04-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124722003928

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