Emergence of the primordial pre-60S from the 90S pre-ribosome
Summary: Synthesis of ribosomes begins in the nucleolus with formation of the 90S pre-ribosome, during which the pre-40S and pre-60S pathways diverge by pre-rRNA cleavage. However, it remains unclear how, after this uncoupling, the earliest pre-60S subunit continues to develop. Here, we reveal a lar...
Main Authors: | Sherif Ismail, Dirk Flemming, Matthias Thoms, José Vicente Gomes-Filho, Lennart Randau, Roland Beckmann, Ed Hurt |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2022-04-01
|
Series: | Cell Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124722003928 |
Similar Items
-
Reconstitution of the complete pathway of ITS2 processing at the pre-ribosome
by: Lisa Fromm, et al.
Published: (2017-11-01) -
Mpp10 represents a platform for the interaction of multiple factors within the 90S pre-ribosome.
by: Bebiana Sá-Moura, et al.
Published: (2017-01-01) -
Cryo-EM structure of a late pre-40S ribosomal subunit from Saccharomyces cerevisiae
by: André Heuer, et al.
Published: (2017-11-01) -
Concurrent remodelling of nucleolar 60S subunit precursors by the Rea1 ATPase and Spb4 RNA helicase
by: Valentin Mitterer, et al.
Published: (2023-03-01) -
Correction: Mpp10 represents a platform for the interaction of multiple factors within the 90S pre-ribosome.
by: Bebiana Sá-Moura, et al.
Published: (2020-01-01)