Clinical Values of the Identified Hub Genes in Systemic Lupus Erythematosus

Clinical Values of the Identified Hub Genes in Systemic Lupus Erythematosus

ObjectiveThis study was conducted to identify the biomarkers and mechanisms associated with systemic lupus erythematosus(SLE) at a transcriptome level.MethodsMicroarray datasets were downloaded, and differentially expressed genes (DEGs) were identified. Enrichment and protein–protein interaction net...

Full description

Bibliographic Details
Main Authors:	Lu Xiao, Feng Zhan, Shudian Lin
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-06-01
Series:	Frontiers in Immunology
Subjects:	systemic lupus erythematosus bioinformatics analysis biomarker receiver operating characteristic curve SLEDAI
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.844025/full

Similar Items

Potential biomarkers for active renal involvement in systemic lupus erythematosus patients
by: Lu Xiao, et al.
Published: (2022-12-01)

Decreased Daily Melatonin Levels in Women with Systemic Lupus Erythematosus - A Short Report
by: Ralitsa Robeva, et al.
Published: (2013-09-01)

Dosagem sérica de adenosina deaminase em lúpus eritematoso sistêmico: ausência de associação com atividade de doença Levels of serum adenosine deaminase in systemic lupus erythematosus: lack of association with disease activity
by: Isabella Lima, et al.
Published: (2005-10-01)

Absolute quantification and characterization of oxylipins in lupus nephritis and systemic lupus erythematosus
by: Jingquan He, et al.
Published: (2022-10-01)

Irreversible organ damages in a cohort of patients with systemic lupus erythematosus (RENAISSANCE)
by: E. A. Aseeva, et al.
Published: (2016-10-01)

CLINICAL VALUE OF BAFF AND APRIL CONCENTRATIONS IN SYSTEMIC LUPUS ERYTHEMATOSUS
by: T. A. Panafidina, et al.
Published: (2016-07-01)

A cross-sectional study on the association of anxiety and depression with the disease activity of systemic lupus erythematosus
by: Jiafen Liao, et al.
Published: (2022-09-01)

Interleukin-6 and disease activity in childhood systemic lupus erythematosus
by: Cahya Dewi Satria, et al.
Published: (2023-11-01)

Improving lupus care index documentation in patients with childhood-onset systemic lupus erythematosus
by: Fatima A. Barbar-Smiley, et al.
Published: (2024-08-01)

Urine and serum interleukin 35 as potential biomarkers of lupus nephritis
by: Mary Atef Nassif
Published: (2021-10-01)

Evaluation of depression and general health assessment among systemic lupus erythematosus patients in relation to disease activity and damage
by: Ahmed Shaaban, et al.
Published: (2022-03-01)

Clinical and serological manifestations associated with interferon-α levels in childhood-onset systemic lupus erythematosus
by: Mariana Postal, et al.
Published: (2012-01-01)

Effects of N-acetylcysteine on systemic lupus erythematosus disease activity and its associated complications: a randomized double-blind clinical trial study
by: Mitra Abbasifard, et al.
Published: (2023-02-01)

Association of urine autoantibodies with disease activity in systemic lupus erythematosus
by: Yuxian Zhang, et al.
Published: (2024-01-01)

Serum Ferritin: A Biomarker of Disease Activity in Lupus Nephritis
by: Kripasindhu Gantait, et al.
Published: (2022-04-01)

Beyond the microbiome: unraveling gut dysbiosis and its impact on systemic lupus erythematosus
by: Yara Safwat Roshdy, et al.
Published: (2025-12-01)

Association of systemic lupus erythematosus standard of care immunosuppressants with glucocorticoid use and disease outcomes: a multicentre cohort study
by: Ricardo Azêdo de Luca Montes, et al.
Published: (2024-05-01)

Performance of a New Instrument for the Measurement of Systemic Lupus Erythematosus Disease Activity: The SLE-DAS
by: Malcolm Koo, et al.
Published: (2023-11-01)

Cytokine profile in childhood-onset systemic lupus erythematosus: a cross-sectional and longitudinal study
by: A. Cavalcanti, et al.

Analysis of the association between the Slit2 biomarker and systemic lupus erythematosus
by: Sara Farrag, et al.
Published: (2024-08-01)

Antibodies to extractable nuclear antigens (ENAS) in systemic lupus erythematosus patients: correlations with clinical manifestations and disease activity
by: Y. Emad, et al.
Published: (2018-07-01)

Altered <i>PTPN22</i> and <i>IL10</i> mRNA Expression Is Associated with Disease Activity and Renal Involvement in Systemic Lupus Erythematosus
by: Ilce Valeria Román-Fernández, et al.
Published: (2022-11-01)

Lupus neuropsiquiátrico
by: Claudia Centurión-Wenninger
Published: (2021-12-01)

Lupus Enteritis: An Uncommon Manifestation of Systemic Lupus Erythematosus as an Initial Presentation
by: Vishal Bodh, et al.
Published: (2017-07-01)

Predictors of severe lupus flare: a prospective follow-up study
by: Alimohammad Fatemi, et al.
Published: (2023-05-01)

Epidemiological, demographic, social, clinical features of manifestations of system red lupus in patients in Kazakhstan
by: B. G. Issayeva, et al.
Published: (2021-03-01)

TGFB1 +869 T > C (rs1800470) variant is independently associated with susceptibility, laboratory activity, and TGF-β1 in patients with systemic lupus erythematosus
by: Nicole Perugini Stadtlober, et al.
Published: (2021-11-01)

Cutaneous lupus erythematosus disease assessment: Highlighting CLE outcome measures
by: Rebecca G. Gaffney, et al.
Published: (2022-10-01)

Urinary microbiome profiling as a non-invasive tool for identifying biomarkers in systemic lupus erythematosus and lupus nephritis
by: Bo Shi, et al.
Published: (2024-12-01)

Alterations in the human oral microbiota in systemic lupus erythematosus
by: Jinyan Guo, et al.
Published: (2023-02-01)

Rapid clearance of cutaneous lesions with anifrolumab in SLE (systemic lupus erythematosus) and DLE (discoid lupus erythematosus)
by: E. Parriel, et al.
Published: (2025-03-01)

Validity of the Systemic Lupus Erythematosus Disease Activity 2000-Glucocorticoid Index, its association with the Physician Global Assessment, and potential association with disease damage
by: Basma M. Medhat, et al.
Published: (2025-01-01)

Immunophenotyping identifies distinct cellular signatures for systemic lupus erythematosus and lupus nephritis
by: Yi Tong V. Aw, et al.
Published: (2023-03-01)

Drug-induced lupus erythematosus
by: Ana L. Gouveia, et al.
Published: (2023-07-01)

Impact of anxiety and depression on disease activity and quality of life in patients with lupus nephritis
by: Ritambra Dadwal, et al.
Published: (2023-04-01)

Predictive factors of psychiatric syndrome in patients with systemic lupus erythematosus
by: Wenqi Geng, et al.
Published: (2024-03-01)

Cutaneous lupus erythematosus of elbows: A distinct entity?
by: Nidhi Singh, et al.
Published: (2016-01-01)

Cutaneous lupus erythematosus: a review of etiopathogenic, clinical, diagnostic and therapeutic aspects
by: Everton Carlos Siviero do Vale, et al.
Published: (2023-06-01)

Fungal gut microbiota dysbiosis in systemic lupus erythematosus
by: Ping Yang, et al.
Published: (2023-04-01)

Direct immunofluorescence in Lupus Erythematosus (LE)
by: Roseli Svartman Isfer, et al.