Vaccines against Genital Herpes: Where Are We?
Genital herpes is a venereal disease caused by herpes simplex virus (HSV). Although HSV symptoms can be reduced with antiviral drugs, there is no cure. Moreover, because HSV infected individuals are often unaware of their infection, it is highly likely that they will transmit HSV to their sexual par...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-07-01
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| Series: | Vaccines |
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| Online Access: | https://www.mdpi.com/2076-393X/8/3/420 |
| _version_ | 1827712200769273856 |
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| author | Hyeon Cheol Kim Heung Kyu Lee |
| author_facet | Hyeon Cheol Kim Heung Kyu Lee |
| author_sort | Hyeon Cheol Kim |
| collection | DOAJ |
| description | Genital herpes is a venereal disease caused by herpes simplex virus (HSV). Although HSV symptoms can be reduced with antiviral drugs, there is no cure. Moreover, because HSV infected individuals are often unaware of their infection, it is highly likely that they will transmit HSV to their sexual partner. Once infected, an individual has to live with HSV for their entire life, and HSV infection can lead to meningitis, encephalitis, and neonatal herpes as a result of vertical transmission. In addition, HSV infection increases the rates of human immunodeficiency virus (HIV) infection and transmission. Because of the high burden of genital herpes, HSV vaccines have been developed, but none have been very successful. In this review, we discuss the current status of genital herpes vaccine development. |
| first_indexed | 2024-03-10T18:10:50Z |
| format | Article |
| id | doaj.art-2737c11cc47c4d13a67cb023485e1457 |
| institution | Directory Open Access Journal |
| issn | 2076-393X |
| language | English |
| last_indexed | 2024-03-10T18:10:50Z |
| publishDate | 2020-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Vaccines |
| spelling | doaj.art-2737c11cc47c4d13a67cb023485e14572023-11-20T08:06:38ZengMDPI AGVaccines2076-393X2020-07-018342010.3390/vaccines8030420Vaccines against Genital Herpes: Where Are We?Hyeon Cheol Kim0Heung Kyu Lee1Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, KoreaGraduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, KoreaGenital herpes is a venereal disease caused by herpes simplex virus (HSV). Although HSV symptoms can be reduced with antiviral drugs, there is no cure. Moreover, because HSV infected individuals are often unaware of their infection, it is highly likely that they will transmit HSV to their sexual partner. Once infected, an individual has to live with HSV for their entire life, and HSV infection can lead to meningitis, encephalitis, and neonatal herpes as a result of vertical transmission. In addition, HSV infection increases the rates of human immunodeficiency virus (HIV) infection and transmission. Because of the high burden of genital herpes, HSV vaccines have been developed, but none have been very successful. In this review, we discuss the current status of genital herpes vaccine development.https://www.mdpi.com/2076-393X/8/3/420genital herpesvaccineherpes simplex virusHSV |
| spellingShingle | Hyeon Cheol Kim Heung Kyu Lee Vaccines against Genital Herpes: Where Are We? Vaccines genital herpes vaccine herpes simplex virus HSV |
| title | Vaccines against Genital Herpes: Where Are We? |
| title_full | Vaccines against Genital Herpes: Where Are We? |
| title_fullStr | Vaccines against Genital Herpes: Where Are We? |
| title_full_unstemmed | Vaccines against Genital Herpes: Where Are We? |
| title_short | Vaccines against Genital Herpes: Where Are We? |
| title_sort | vaccines against genital herpes where are we |
| topic | genital herpes vaccine herpes simplex virus HSV |
| url | https://www.mdpi.com/2076-393X/8/3/420 |
| work_keys_str_mv | AT hyeoncheolkim vaccinesagainstgenitalherpeswherearewe AT heungkyulee vaccinesagainstgenitalherpeswherearewe |