Interleukin 1 alpha administration is neuroprotective and neuro-restorative following experimental ischemic stroke

Interleukin 1 alpha administration is neuroprotective and neuro-restorative following experimental ischemic stroke

Abstract Background Stroke remains a leading cause of death and disability worldwide despite recent treatment breakthroughs. A primary event in stroke pathogenesis is the development of a potent and deleterious local and peripheral inflammatory response regulated by the pro-inflammatory cytokine int...

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Bibliographic Details
Main Authors: Kathleen E. Salmeron, Michael E. Maniskas, Danielle N. Edwards, Raymond Wong, Ivana Rajkovic, Amanda Trout, Abir A. Rahman, Samantha Hamilton, Justin F. Fraser, Emmanuel Pinteaux, Gregory J. Bix
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Journal of Neuroinflammation
Subjects:
Interleukin 1 alpha
Stroke
Therapeutic
Neuroprotection
Neurorepair
Angiogenesis
Online Access:http://link.springer.com/article/10.1186/s12974-019-1599-9

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