A pediatric case series of invasive pneumococcal disease caused by S.Pneumonia serotype-19A despite full dose vaccination
Streptococcus pneumoniae is the leading cause of community-acquired pneumonia and bacterial meningitis in children. Although pneumococcal conjugate vaccines (PCVs) are commonly available, invasive pneumococcal disease (IPD) still remains a life-threatening complication. Serotype 19A has high invasiv...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2023-08-01
|
| Series: | Human Vaccines & Immunotherapeutics |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/21645515.2023.2219186 |
| _version_ | 1797673028940726272 |
|---|---|
| author | Burcu Ceylan Cura Yayla Tugba Bedir Demirdag Emine Akkuzu Nursel Kara Hasan Tezer Anıl Tapisiz |
| author_facet | Burcu Ceylan Cura Yayla Tugba Bedir Demirdag Emine Akkuzu Nursel Kara Hasan Tezer Anıl Tapisiz |
| author_sort | Burcu Ceylan Cura Yayla |
| collection | DOAJ |
| description | Streptococcus pneumoniae is the leading cause of community-acquired pneumonia and bacterial meningitis in children. Although pneumococcal conjugate vaccines (PCVs) are commonly available, invasive pneumococcal disease (IPD) still remains a life-threatening complication. Serotype 19A has high invasive potential and is capable of causing extensive and destructive lung disease. This strain has greater invasive potential, may have a growth advantage over other pneumococcal serotypes in normally sterile sites, and is often resistant to multiple antibiotics. Although being a component of PCV13 vaccine, serotype 19A may still be seen in fully vaccinated children and can cause invasive disease. Herein, we present four cases of IPD caused by S. pneumoniae serotype 19A who received the full regimen of PCV13 vaccination. |
| first_indexed | 2024-03-11T21:39:32Z |
| format | Article |
| id | doaj.art-273ed7b64409486d884ed64c6240481e |
| institution | Directory Open Access Journal |
| issn | 2164-5515 2164-554X |
| language | English |
| last_indexed | 2024-03-11T21:39:32Z |
| publishDate | 2023-08-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Human Vaccines & Immunotherapeutics |
| spelling | doaj.art-273ed7b64409486d884ed64c6240481e2023-09-26T13:25:50ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2023-08-0119210.1080/21645515.2023.22191862219186A pediatric case series of invasive pneumococcal disease caused by S.Pneumonia serotype-19A despite full dose vaccinationBurcu Ceylan Cura Yayla0Tugba Bedir Demirdag1Emine Akkuzu2Nursel Kara3Hasan Tezer4Anıl Tapisiz5University of Health Science Ankara Training and Research HospitalGazi University Faculty of MedicineGazi University Faculty of MedicineGazi University Faculty of MedicineGazi University Faculty of MedicineGazi University Faculty of MedicineStreptococcus pneumoniae is the leading cause of community-acquired pneumonia and bacterial meningitis in children. Although pneumococcal conjugate vaccines (PCVs) are commonly available, invasive pneumococcal disease (IPD) still remains a life-threatening complication. Serotype 19A has high invasive potential and is capable of causing extensive and destructive lung disease. This strain has greater invasive potential, may have a growth advantage over other pneumococcal serotypes in normally sterile sites, and is often resistant to multiple antibiotics. Although being a component of PCV13 vaccine, serotype 19A may still be seen in fully vaccinated children and can cause invasive disease. Herein, we present four cases of IPD caused by S. pneumoniae serotype 19A who received the full regimen of PCV13 vaccination.http://dx.doi.org/10.1080/21645515.2023.2219186pneumococci serotype 19invasive pneumococcal diseasepediatric |
| spellingShingle | Burcu Ceylan Cura Yayla Tugba Bedir Demirdag Emine Akkuzu Nursel Kara Hasan Tezer Anıl Tapisiz A pediatric case series of invasive pneumococcal disease caused by S.Pneumonia serotype-19A despite full dose vaccination Human Vaccines & Immunotherapeutics pneumococci serotype 19 invasive pneumococcal disease pediatric |
| title | A pediatric case series of invasive pneumococcal disease caused by S.Pneumonia serotype-19A despite full dose vaccination |
| title_full | A pediatric case series of invasive pneumococcal disease caused by S.Pneumonia serotype-19A despite full dose vaccination |
| title_fullStr | A pediatric case series of invasive pneumococcal disease caused by S.Pneumonia serotype-19A despite full dose vaccination |
| title_full_unstemmed | A pediatric case series of invasive pneumococcal disease caused by S.Pneumonia serotype-19A despite full dose vaccination |
| title_short | A pediatric case series of invasive pneumococcal disease caused by S.Pneumonia serotype-19A despite full dose vaccination |
| title_sort | pediatric case series of invasive pneumococcal disease caused by s pneumonia serotype 19a despite full dose vaccination |
| topic | pneumococci serotype 19 invasive pneumococcal disease pediatric |
| url | http://dx.doi.org/10.1080/21645515.2023.2219186 |
| work_keys_str_mv | AT burcuceylancurayayla apediatriccaseseriesofinvasivepneumococcaldiseasecausedbyspneumoniaserotype19adespitefulldosevaccination AT tugbabedirdemirdag apediatriccaseseriesofinvasivepneumococcaldiseasecausedbyspneumoniaserotype19adespitefulldosevaccination AT emineakkuzu apediatriccaseseriesofinvasivepneumococcaldiseasecausedbyspneumoniaserotype19adespitefulldosevaccination AT nurselkara apediatriccaseseriesofinvasivepneumococcaldiseasecausedbyspneumoniaserotype19adespitefulldosevaccination AT hasantezer apediatriccaseseriesofinvasivepneumococcaldiseasecausedbyspneumoniaserotype19adespitefulldosevaccination AT anıltapisiz apediatriccaseseriesofinvasivepneumococcaldiseasecausedbyspneumoniaserotype19adespitefulldosevaccination AT burcuceylancurayayla pediatriccaseseriesofinvasivepneumococcaldiseasecausedbyspneumoniaserotype19adespitefulldosevaccination AT tugbabedirdemirdag pediatriccaseseriesofinvasivepneumococcaldiseasecausedbyspneumoniaserotype19adespitefulldosevaccination AT emineakkuzu pediatriccaseseriesofinvasivepneumococcaldiseasecausedbyspneumoniaserotype19adespitefulldosevaccination AT nurselkara pediatriccaseseriesofinvasivepneumococcaldiseasecausedbyspneumoniaserotype19adespitefulldosevaccination AT hasantezer pediatriccaseseriesofinvasivepneumococcaldiseasecausedbyspneumoniaserotype19adespitefulldosevaccination AT anıltapisiz pediatriccaseseriesofinvasivepneumococcaldiseasecausedbyspneumoniaserotype19adespitefulldosevaccination |