Current Applications and New Perspectives in Optical Coherence Tomography (OCT) Coronary Atherosclerotic Plaque Assessment: From PCI Optimization to Pharmacological Treatment Guidance
Since its ability to precisely characterized atherosclerotic plaque phenotypes, to tailor stent implantation, as well as to guide both complex percutaneous coronary interventions (PCI) and invasive diagnostic work-ups (e.g., spontaneous coronary dissections or myocardial infarction with non-obstruct...
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-02-01
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| Series: | Photonics |
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| Online Access: | https://www.mdpi.com/2304-6732/10/2/158 |
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| author | Michele Mattia Viscusi Ylenia La Porta Giuseppe Migliaro Gian Marco Gargano Annunziata Nusca Laura Gatto Simone Budassi Luca Paolucci Fabio Mangiacapra Elisabetta Ricottini Rosetta Melfi Raffaele Rinaldi Francesco Prati Gian Paolo Ussia Francesco Grigioni |
| author_facet | Michele Mattia Viscusi Ylenia La Porta Giuseppe Migliaro Gian Marco Gargano Annunziata Nusca Laura Gatto Simone Budassi Luca Paolucci Fabio Mangiacapra Elisabetta Ricottini Rosetta Melfi Raffaele Rinaldi Francesco Prati Gian Paolo Ussia Francesco Grigioni |
| author_sort | Michele Mattia Viscusi |
| collection | DOAJ |
| description | Since its ability to precisely characterized atherosclerotic plaque phenotypes, to tailor stent implantation, as well as to guide both complex percutaneous coronary interventions (PCI) and invasive diagnostic work-ups (e.g., spontaneous coronary dissections or myocardial infarction with non-obstructive arteries), the adoption of optical coherence tomography (OCT) was raised in the past decades in order to provide complementary information to the traditional angiography and to overcome its limitations. However, the impact of OCT on daily clinical practice is currently modest, firstly because of the lack of both standardized algorithms of PCI guidance and data from prospective clinical trials. Therefore, the aim of our narrative review is to provide a comprehensive overview of the basic OCT interpretation, to summarize the evidence supporting the OCT guidance procedures and applications, to discuss its current limitations, and to highlight the knowledge gaps that need to be filled with more robust evidence. |
| first_indexed | 2024-03-11T08:15:35Z |
| format | Article |
| id | doaj.art-273f806e4b414c3ea26ec8cddf1ea7a6 |
| institution | Directory Open Access Journal |
| issn | 2304-6732 |
| language | English |
| last_indexed | 2024-03-11T08:15:35Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Photonics |
| spelling | doaj.art-273f806e4b414c3ea26ec8cddf1ea7a62023-11-16T22:45:10ZengMDPI AGPhotonics2304-67322023-02-0110215810.3390/photonics10020158Current Applications and New Perspectives in Optical Coherence Tomography (OCT) Coronary Atherosclerotic Plaque Assessment: From PCI Optimization to Pharmacological Treatment GuidanceMichele Mattia Viscusi0Ylenia La Porta1Giuseppe Migliaro2Gian Marco Gargano3Annunziata Nusca4Laura Gatto5Simone Budassi6Luca Paolucci7Fabio Mangiacapra8Elisabetta Ricottini9Rosetta Melfi10Raffaele Rinaldi11Francesco Prati12Gian Paolo Ussia13Francesco Grigioni14Unit of Cardiovascular Science, Department of Medicine, Campus Bio-Medico University, 00128 Rome, ItalyUnit of Cardiovascular Science, Department of Medicine, Campus Bio-Medico University, 00128 Rome, ItalyUnit of Cardiovascular Science, Department of Medicine, Campus Bio-Medico University, 00128 Rome, ItalyUnit of Cardiovascular Science, Department of Medicine, Campus Bio-Medico University, 00128 Rome, ItalyUnit of Cardiovascular Science, Department of Medicine, Campus Bio-Medico University, 00128 Rome, ItalySan Giovanni Addolorata Hospital, Cardiology Department, 00184 Rome, ItalySan Giovanni Addolorata Hospital, Cardiology Department, 00184 Rome, ItalyUnit of Cardiovascular Science, Department of Medicine, Campus Bio-Medico University, 00128 Rome, ItalyUnit of Cardiovascular Science, Department of Medicine, Campus Bio-Medico University, 00128 Rome, ItalyUnit of Cardiovascular Science, Department of Medicine, Campus Bio-Medico University, 00128 Rome, ItalyUnit of Cardiovascular Science, Department of Medicine, Campus Bio-Medico University, 00128 Rome, ItalyUnit of Cardiovascular Science, Department of Medicine, Campus Bio-Medico University, 00128 Rome, ItalySan Giovanni Addolorata Hospital, Cardiology Department, 00184 Rome, ItalyUnit of Cardiovascular Science, Department of Medicine, Campus Bio-Medico University, 00128 Rome, ItalyUnit of Cardiovascular Science, Department of Medicine, Campus Bio-Medico University, 00128 Rome, ItalySince its ability to precisely characterized atherosclerotic plaque phenotypes, to tailor stent implantation, as well as to guide both complex percutaneous coronary interventions (PCI) and invasive diagnostic work-ups (e.g., spontaneous coronary dissections or myocardial infarction with non-obstructive arteries), the adoption of optical coherence tomography (OCT) was raised in the past decades in order to provide complementary information to the traditional angiography and to overcome its limitations. However, the impact of OCT on daily clinical practice is currently modest, firstly because of the lack of both standardized algorithms of PCI guidance and data from prospective clinical trials. Therefore, the aim of our narrative review is to provide a comprehensive overview of the basic OCT interpretation, to summarize the evidence supporting the OCT guidance procedures and applications, to discuss its current limitations, and to highlight the knowledge gaps that need to be filled with more robust evidence.https://www.mdpi.com/2304-6732/10/2/158OCToptical coherence tomographyPCIpercutaneous coronary interventionatherosclerotic plaque assessment |
| spellingShingle | Michele Mattia Viscusi Ylenia La Porta Giuseppe Migliaro Gian Marco Gargano Annunziata Nusca Laura Gatto Simone Budassi Luca Paolucci Fabio Mangiacapra Elisabetta Ricottini Rosetta Melfi Raffaele Rinaldi Francesco Prati Gian Paolo Ussia Francesco Grigioni Current Applications and New Perspectives in Optical Coherence Tomography (OCT) Coronary Atherosclerotic Plaque Assessment: From PCI Optimization to Pharmacological Treatment Guidance Photonics OCT optical coherence tomography PCI percutaneous coronary intervention atherosclerotic plaque assessment |
| title | Current Applications and New Perspectives in Optical Coherence Tomography (OCT) Coronary Atherosclerotic Plaque Assessment: From PCI Optimization to Pharmacological Treatment Guidance |
| title_full | Current Applications and New Perspectives in Optical Coherence Tomography (OCT) Coronary Atherosclerotic Plaque Assessment: From PCI Optimization to Pharmacological Treatment Guidance |
| title_fullStr | Current Applications and New Perspectives in Optical Coherence Tomography (OCT) Coronary Atherosclerotic Plaque Assessment: From PCI Optimization to Pharmacological Treatment Guidance |
| title_full_unstemmed | Current Applications and New Perspectives in Optical Coherence Tomography (OCT) Coronary Atherosclerotic Plaque Assessment: From PCI Optimization to Pharmacological Treatment Guidance |
| title_short | Current Applications and New Perspectives in Optical Coherence Tomography (OCT) Coronary Atherosclerotic Plaque Assessment: From PCI Optimization to Pharmacological Treatment Guidance |
| title_sort | current applications and new perspectives in optical coherence tomography oct coronary atherosclerotic plaque assessment from pci optimization to pharmacological treatment guidance |
| topic | OCT optical coherence tomography PCI percutaneous coronary intervention atherosclerotic plaque assessment |
| url | https://www.mdpi.com/2304-6732/10/2/158 |
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