Detection of Diphtheritic Polyneuropathy by Acute Flaccid Paralysis Surveillance, India

Diphtheritic polyneuropathy is a vaccine-preventable illness caused by exotoxin-producing strains of Corynebacterium diphtheriae. We present a retrospective convenience case series of 15 children (6 girls) <15 years of age (mean age 5.2 years, case-fatality rate 53%, and 1 additional case-patient...

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Main Authors: Farrah J. Mateen, Sunil Bahl, Ajay Khera, Roland W. Sutter
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2013-09-01
Series:Emerging Infectious Diseases
Subjects:
Online Access:https://wwwnc.cdc.gov/eid/article/19/9/13-0117_article
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author Farrah J. Mateen
Sunil Bahl
Ajay Khera
Roland W. Sutter
author_facet Farrah J. Mateen
Sunil Bahl
Ajay Khera
Roland W. Sutter
author_sort Farrah J. Mateen
collection DOAJ
description Diphtheritic polyneuropathy is a vaccine-preventable illness caused by exotoxin-producing strains of Corynebacterium diphtheriae. We present a retrospective convenience case series of 15 children (6 girls) <15 years of age (mean age 5.2 years, case-fatality rate 53%, and 1 additional case-patient who was ventilator dependent at the time of last follow-up; median follow-up period 60 days) with signs and symptoms suggestive of diphtheritic polyneuropathy. All cases were identified through national acute flaccid paralysis surveillance, which was designed to detect poliomyelitis in India during 2002–2008. We also report data on detection of diphtheritic polyneuropathy compared with other causes of acute flaccid paralysis identified by this surveillance system.
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spelling doaj.art-27436c54073b4085ac0d437ba0604eeb2022-12-22T00:16:11ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592013-09-011991370137310.3201/eid1909.130117Detection of Diphtheritic Polyneuropathy by Acute Flaccid Paralysis Surveillance, IndiaFarrah J. MateenSunil BahlAjay KheraRoland W. SutterDiphtheritic polyneuropathy is a vaccine-preventable illness caused by exotoxin-producing strains of Corynebacterium diphtheriae. We present a retrospective convenience case series of 15 children (6 girls) <15 years of age (mean age 5.2 years, case-fatality rate 53%, and 1 additional case-patient who was ventilator dependent at the time of last follow-up; median follow-up period 60 days) with signs and symptoms suggestive of diphtheritic polyneuropathy. All cases were identified through national acute flaccid paralysis surveillance, which was designed to detect poliomyelitis in India during 2002–2008. We also report data on detection of diphtheritic polyneuropathy compared with other causes of acute flaccid paralysis identified by this surveillance system.https://wwwnc.cdc.gov/eid/article/19/9/13-0117_articlediphtheriaparalysisdiphtheritic polyneuropathyneurologyGuillain-Barré syndromeimmunization
spellingShingle Farrah J. Mateen
Sunil Bahl
Ajay Khera
Roland W. Sutter
Detection of Diphtheritic Polyneuropathy by Acute Flaccid Paralysis Surveillance, India
Emerging Infectious Diseases
diphtheria
paralysis
diphtheritic polyneuropathy
neurology
Guillain-Barré syndrome
immunization
title Detection of Diphtheritic Polyneuropathy by Acute Flaccid Paralysis Surveillance, India
title_full Detection of Diphtheritic Polyneuropathy by Acute Flaccid Paralysis Surveillance, India
title_fullStr Detection of Diphtheritic Polyneuropathy by Acute Flaccid Paralysis Surveillance, India
title_full_unstemmed Detection of Diphtheritic Polyneuropathy by Acute Flaccid Paralysis Surveillance, India
title_short Detection of Diphtheritic Polyneuropathy by Acute Flaccid Paralysis Surveillance, India
title_sort detection of diphtheritic polyneuropathy by acute flaccid paralysis surveillance india
topic diphtheria
paralysis
diphtheritic polyneuropathy
neurology
Guillain-Barré syndrome
immunization
url https://wwwnc.cdc.gov/eid/article/19/9/13-0117_article
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