Effectiveness of non-invasive ventilation in acute respiratory failure of obese patients: a brief narrative review

Non-invasive ventilation (NIV) has been used successfully for the management of acute respiratory failure (ARF) more often in the last two decades compared to prior decades; nevertheless, NIV can have failure rates ranging from 5% to 50%. However, there are particular groups of patients that are mor...

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Main Authors: Maurizio Alessandro Cavalleri, Elena Barbagelata, Marco Scudeletti, Antonello Nicolini
Format: Article
Language:English
Published: PAGEPress Publications 2018-03-01
Series:Italian Journal of Medicine
Subjects:
Online Access:http://www.italjmed.org/index.php/ijm/article/view/916
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author Maurizio Alessandro Cavalleri
Elena Barbagelata
Marco Scudeletti
Antonello Nicolini
author_facet Maurizio Alessandro Cavalleri
Elena Barbagelata
Marco Scudeletti
Antonello Nicolini
author_sort Maurizio Alessandro Cavalleri
collection DOAJ
description Non-invasive ventilation (NIV) has been used successfully for the management of acute respiratory failure (ARF) more often in the last two decades compared to prior decades; nevertheless, NIV can have failure rates ranging from 5% to 50%. However, there are particular groups of patients that are more likely to benefit from NIV. One of these groups is patients with hypoventilation syndrome (OHS). The aim of this review is to seek evaluation of the effectiveness of NIV in acute setting. Only a few studies have investigated NIV success or failure in OHS patients. More than 30% of them were diagnosed when hospitalized for ARF. NIV rarely failed in reversing ARF. OHS patients who exhibited early NIV failure had a high severity score and a low HCO3 level at admission; more than half of hypercapnic patients with decompensated OHS exhibited a delayed but successful response to NIV. Patients with decompensation of OHS have a better prognosis and response to NIV than other hypercapnic patients. They require more aggressive NIV settings, a longer time to reduce PaCO2 levels, and more frequently a delayed but successful response to NIV.
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spelling doaj.art-2745275a61694def8cc20bd8b24e2a522023-12-02T15:03:21ZengPAGEPress PublicationsItalian Journal of Medicine1877-93441877-93522018-03-011215910.4081/itjm.2018.916662Effectiveness of non-invasive ventilation in acute respiratory failure of obese patients: a brief narrative reviewMaurizio Alessandro Cavalleri0Elena Barbagelata1Marco Scudeletti2Antonello Nicolini3Department of Internal Medicine, General Hospital, Sestri Levante (GE)Department of Internal Medicine, General Hospital, Sestri Levante (GE)Department of Internal Medicine, General Hospital, Sestri Levante (GE)Department of Internal Medicine, General Hospital, Sestri Levante (GE)Non-invasive ventilation (NIV) has been used successfully for the management of acute respiratory failure (ARF) more often in the last two decades compared to prior decades; nevertheless, NIV can have failure rates ranging from 5% to 50%. However, there are particular groups of patients that are more likely to benefit from NIV. One of these groups is patients with hypoventilation syndrome (OHS). The aim of this review is to seek evaluation of the effectiveness of NIV in acute setting. Only a few studies have investigated NIV success or failure in OHS patients. More than 30% of them were diagnosed when hospitalized for ARF. NIV rarely failed in reversing ARF. OHS patients who exhibited early NIV failure had a high severity score and a low HCO3 level at admission; more than half of hypercapnic patients with decompensated OHS exhibited a delayed but successful response to NIV. Patients with decompensation of OHS have a better prognosis and response to NIV than other hypercapnic patients. They require more aggressive NIV settings, a longer time to reduce PaCO2 levels, and more frequently a delayed but successful response to NIV.http://www.italjmed.org/index.php/ijm/article/view/916Obesity-hypoventilation syndromecritically ill obese patientsnon-invasive ventilationlate failure.
spellingShingle Maurizio Alessandro Cavalleri
Elena Barbagelata
Marco Scudeletti
Antonello Nicolini
Effectiveness of non-invasive ventilation in acute respiratory failure of obese patients: a brief narrative review
Italian Journal of Medicine
Obesity-hypoventilation syndrome
critically ill obese patients
non-invasive ventilation
late failure.
title Effectiveness of non-invasive ventilation in acute respiratory failure of obese patients: a brief narrative review
title_full Effectiveness of non-invasive ventilation in acute respiratory failure of obese patients: a brief narrative review
title_fullStr Effectiveness of non-invasive ventilation in acute respiratory failure of obese patients: a brief narrative review
title_full_unstemmed Effectiveness of non-invasive ventilation in acute respiratory failure of obese patients: a brief narrative review
title_short Effectiveness of non-invasive ventilation in acute respiratory failure of obese patients: a brief narrative review
title_sort effectiveness of non invasive ventilation in acute respiratory failure of obese patients a brief narrative review
topic Obesity-hypoventilation syndrome
critically ill obese patients
non-invasive ventilation
late failure.
url http://www.italjmed.org/index.php/ijm/article/view/916
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AT marcoscudeletti effectivenessofnoninvasiveventilationinacuterespiratoryfailureofobesepatientsabriefnarrativereview
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