Titanium-Tantalum Alloy Surface Modification by Hydroxyapatite Layer on TiO2 Nanotubes: Effect on Microbial Activity
Abstract One of the major health security challenges of the 21st century is the occurrence of microbial infections and bacterial complications that could affect 10 million people by 2050. On the biomaterial field, implant metallic currently replaces partial or total body parts and can fail to be int...
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| Format: | Article |
| Language: | English |
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Associação Brasileira de Metalurgia e Materiais (ABM); Associação Brasileira de Cerâmica (ABC); Associação Brasileira de Polímeros (ABPol)
2021-10-01
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| Series: | Materials Research |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392021000600226&tlng=en |
| _version_ | 1818975319942496256 |
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| author | Patricia Capellato Lucas V. B. Vasconcelos Filipe B. Vilela Gilza Carla Ribeiro Cristiane A. P. Correia Gilbert Silva Daniela Sachs André L. R. Rangel Cecilia A. de C. Zavaglia Ana P. R. Alves Claro |
| author_facet | Patricia Capellato Lucas V. B. Vasconcelos Filipe B. Vilela Gilza Carla Ribeiro Cristiane A. P. Correia Gilbert Silva Daniela Sachs André L. R. Rangel Cecilia A. de C. Zavaglia Ana P. R. Alves Claro |
| author_sort | Patricia Capellato |
| collection | DOAJ |
| description | Abstract One of the major health security challenges of the 21st century is the occurrence of microbial infections and bacterial complications that could affect 10 million people by 2050. On the biomaterial field, implant metallic currently replaces partial or total body parts and can fail to be integrated into the body due to infections. This study performs two combined surface modifications on Ti-30Ta alloy, in order to obtain an infection-resistance and osseointegration surface on metallic implants to be tested within bacterial biofilm. The Group 1 investigated surface modifications by the anodization process in the electrolyte glycerol + NH4F 0.25% at 30V- 9 hours and annealed in 530°C (5°C/min). The Group 2 underwent the same process as Group 1 and, additionally, the samples were immersed in 0.3 M CaCl2 and 0.5 M Na2HPO4 solutions for hydroxyapatite growth. The substrate was characterized using scanning electron microscopy (SEM), X-ray diffractometer (XRD) and dynamic contact angle. S. epidermidis bacterial adhesion and biofilm formation. The results indicated that the Group 1 shows a higher antimicrobial activity, hydrophilic behavior and potential to be used for metallic implant applications. The Group 2 with the hydroxyapatite film coating did not have an improvement in the antimicrobial response. |
| first_indexed | 2024-12-20T15:54:04Z |
| format | Article |
| id | doaj.art-274eaf5374a24708872aa4ed402ab8eb |
| institution | Directory Open Access Journal |
| issn | 1516-1439 |
| language | English |
| last_indexed | 2024-12-20T15:54:04Z |
| publishDate | 2021-10-01 |
| publisher | Associação Brasileira de Metalurgia e Materiais (ABM); Associação Brasileira de Cerâmica (ABC); Associação Brasileira de Polímeros (ABPol) |
| record_format | Article |
| series | Materials Research |
| spelling | doaj.art-274eaf5374a24708872aa4ed402ab8eb2022-12-21T19:34:32ZengAssociação Brasileira de Metalurgia e Materiais (ABM); Associação Brasileira de Cerâmica (ABC); Associação Brasileira de Polímeros (ABPol)Materials Research1516-14392021-10-0124610.1590/1980-5373-mr-2021-0285Titanium-Tantalum Alloy Surface Modification by Hydroxyapatite Layer on TiO2 Nanotubes: Effect on Microbial ActivityPatricia Capellatohttps://orcid.org/0000-0002-6397-5820Lucas V. B. VasconcelosFilipe B. Vilelahttps://orcid.org/0000-0003-0909-0893Gilza Carla RibeiroCristiane A. P. CorreiaGilbert SilvaDaniela SachsAndré L. R. RangelCecilia A. de C. ZavagliaAna P. R. Alves ClaroAbstract One of the major health security challenges of the 21st century is the occurrence of microbial infections and bacterial complications that could affect 10 million people by 2050. On the biomaterial field, implant metallic currently replaces partial or total body parts and can fail to be integrated into the body due to infections. This study performs two combined surface modifications on Ti-30Ta alloy, in order to obtain an infection-resistance and osseointegration surface on metallic implants to be tested within bacterial biofilm. The Group 1 investigated surface modifications by the anodization process in the electrolyte glycerol + NH4F 0.25% at 30V- 9 hours and annealed in 530°C (5°C/min). The Group 2 underwent the same process as Group 1 and, additionally, the samples were immersed in 0.3 M CaCl2 and 0.5 M Na2HPO4 solutions for hydroxyapatite growth. The substrate was characterized using scanning electron microscopy (SEM), X-ray diffractometer (XRD) and dynamic contact angle. S. epidermidis bacterial adhesion and biofilm formation. The results indicated that the Group 1 shows a higher antimicrobial activity, hydrophilic behavior and potential to be used for metallic implant applications. The Group 2 with the hydroxyapatite film coating did not have an improvement in the antimicrobial response.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392021000600226&tlng=enTitanium alloysurface modificationantimicrobial activitynanotubes coatingHydroxyapatite |
| spellingShingle | Patricia Capellato Lucas V. B. Vasconcelos Filipe B. Vilela Gilza Carla Ribeiro Cristiane A. P. Correia Gilbert Silva Daniela Sachs André L. R. Rangel Cecilia A. de C. Zavaglia Ana P. R. Alves Claro Titanium-Tantalum Alloy Surface Modification by Hydroxyapatite Layer on TiO2 Nanotubes: Effect on Microbial Activity Materials Research Titanium alloy surface modification antimicrobial activity nanotubes coating Hydroxyapatite |
| title | Titanium-Tantalum Alloy Surface Modification by Hydroxyapatite Layer on TiO2 Nanotubes: Effect on Microbial Activity |
| title_full | Titanium-Tantalum Alloy Surface Modification by Hydroxyapatite Layer on TiO2 Nanotubes: Effect on Microbial Activity |
| title_fullStr | Titanium-Tantalum Alloy Surface Modification by Hydroxyapatite Layer on TiO2 Nanotubes: Effect on Microbial Activity |
| title_full_unstemmed | Titanium-Tantalum Alloy Surface Modification by Hydroxyapatite Layer on TiO2 Nanotubes: Effect on Microbial Activity |
| title_short | Titanium-Tantalum Alloy Surface Modification by Hydroxyapatite Layer on TiO2 Nanotubes: Effect on Microbial Activity |
| title_sort | titanium tantalum alloy surface modification by hydroxyapatite layer on tio2 nanotubes effect on microbial activity |
| topic | Titanium alloy surface modification antimicrobial activity nanotubes coating Hydroxyapatite |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392021000600226&tlng=en |
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