A one-pot protocol for iron-catalyzed decarbonylative borylation of aryl and alkyl carboxylic acids
Summary: We present a protocol for the eco-friendly synthesis of aryl and alkyl boronic esters from aryl and alkyl carboxylic acids. We describe steps for aryl and alkyl carboxylates preparation. We further detail procedures for the synthesis of borylated products using aryl and alkyl carboxylates t...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-12-01
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| Series: | STAR Protocols |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666166722007894 |
| _version_ | 1811199429671124992 |
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| author | Mei Bai Shasha Geng Shuo Chen Zhengli Liu Zhang Feng |
| author_facet | Mei Bai Shasha Geng Shuo Chen Zhengli Liu Zhang Feng |
| author_sort | Mei Bai |
| collection | DOAJ |
| description | Summary: We present a protocol for the eco-friendly synthesis of aryl and alkyl boronic esters from aryl and alkyl carboxylic acids. We describe steps for aryl and alkyl carboxylates preparation. We further detail procedures for the synthesis of borylated products using aryl and alkyl carboxylates through iron-catalyzed decarbonylation at 100°C–130°C, followed by purification of the crude products by flash column chromatography.For complete details on the use and execution of this protocol, please refer to Wen et al. (2022).1 : Publisher’s note: Undertaking any experimental protocol requires adherence to local institutional guidelines for laboratory safety and ethics. |
| first_indexed | 2024-04-12T01:47:57Z |
| format | Article |
| id | doaj.art-274fbc45746740f0bb86496bf4ada756 |
| institution | Directory Open Access Journal |
| issn | 2666-1667 |
| language | English |
| last_indexed | 2024-04-12T01:47:57Z |
| publishDate | 2022-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | STAR Protocols |
| spelling | doaj.art-274fbc45746740f0bb86496bf4ada7562022-12-22T03:53:00ZengElsevierSTAR Protocols2666-16672022-12-0134101909A one-pot protocol for iron-catalyzed decarbonylative borylation of aryl and alkyl carboxylic acidsMei Bai0Shasha Geng1Shuo Chen2Zhengli Liu3Zhang Feng4Key Laboratory of Biocatalysis & Chiral Drug Synthesis of Guizhou Province, Generic Drug Research Center of Guizhou Province, School of Pharmacy, Zunyi Medical University, Zunyi, Guizhou 563003, China; Corresponding authorChongqing Key Laboratory of Natural Product Synthesis and Drug Research, School of Pharmaceutical Sciences, Chongqing University, Chongqing 401331, ChinaChongqing Key Laboratory of Natural Product Synthesis and Drug Research, School of Pharmaceutical Sciences, Chongqing University, Chongqing 401331, ChinaChongqing Key Laboratory of Natural Product Synthesis and Drug Research, School of Pharmaceutical Sciences, Chongqing University, Chongqing 401331, ChinaChongqing Key Laboratory of Natural Product Synthesis and Drug Research, School of Pharmaceutical Sciences, Chongqing University, Chongqing 401331, China; Corresponding authorSummary: We present a protocol for the eco-friendly synthesis of aryl and alkyl boronic esters from aryl and alkyl carboxylic acids. We describe steps for aryl and alkyl carboxylates preparation. We further detail procedures for the synthesis of borylated products using aryl and alkyl carboxylates through iron-catalyzed decarbonylation at 100°C–130°C, followed by purification of the crude products by flash column chromatography.For complete details on the use and execution of this protocol, please refer to Wen et al. (2022).1 : Publisher’s note: Undertaking any experimental protocol requires adherence to local institutional guidelines for laboratory safety and ethics.http://www.sciencedirect.com/science/article/pii/S2666166722007894Structural BiologyChemistryMaterial sciencesEnvironmental sciences |
| spellingShingle | Mei Bai Shasha Geng Shuo Chen Zhengli Liu Zhang Feng A one-pot protocol for iron-catalyzed decarbonylative borylation of aryl and alkyl carboxylic acids STAR Protocols Structural Biology Chemistry Material sciences Environmental sciences |
| title | A one-pot protocol for iron-catalyzed decarbonylative borylation of aryl and alkyl carboxylic acids |
| title_full | A one-pot protocol for iron-catalyzed decarbonylative borylation of aryl and alkyl carboxylic acids |
| title_fullStr | A one-pot protocol for iron-catalyzed decarbonylative borylation of aryl and alkyl carboxylic acids |
| title_full_unstemmed | A one-pot protocol for iron-catalyzed decarbonylative borylation of aryl and alkyl carboxylic acids |
| title_short | A one-pot protocol for iron-catalyzed decarbonylative borylation of aryl and alkyl carboxylic acids |
| title_sort | one pot protocol for iron catalyzed decarbonylative borylation of aryl and alkyl carboxylic acids |
| topic | Structural Biology Chemistry Material sciences Environmental sciences |
| url | http://www.sciencedirect.com/science/article/pii/S2666166722007894 |
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