Dental health of patients with X-linked hypophosphatemia: A controlled study
ObjectiveThe present study compared the dental health of patients with X-linked hypophosphatemia (XLH) with healthy age- and gender-matched controls to increase our knowledge of the impact of XLH on oral health.Materials and methodsTwenty-two adult patients with XLH in the Stockholm region of Sweden...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-03-01
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| Series: | Frontiers in Oral Health |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/froh.2023.1087761/full |
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| author | Amila Larsson Amila Larsson Tobias Regnstrand Pia Skott Pia Skott Outi Mäkitie Outi Mäkitie Outi Mäkitie Sigridur Björnsdottir Sigridur Björnsdottir Karin Garming-Legert |
| author_facet | Amila Larsson Amila Larsson Tobias Regnstrand Pia Skott Pia Skott Outi Mäkitie Outi Mäkitie Outi Mäkitie Sigridur Björnsdottir Sigridur Björnsdottir Karin Garming-Legert |
| author_sort | Amila Larsson |
| collection | DOAJ |
| description | ObjectiveThe present study compared the dental health of patients with X-linked hypophosphatemia (XLH) with healthy age- and gender-matched controls to increase our knowledge of the impact of XLH on oral health.Materials and methodsTwenty-two adult patients with XLH in the Stockholm region of Sweden were referred to the Department of Orofacial Medicine at Karolinska Institutet for an extended clinical and radiological examination. Pre-existing radiologic examinations of 44 healthy age- and gender-matched controls were retrieved from the Department of Oral Radiology, at Karolinska Institutet.ResultsThe 22 patients with XLH (15 females, median age 38 years, range 20–71; 7 males, median age 49 years, range 24–67) had a significantly higher number of root-filled teeth compared to healthy controls (p = .001). In the XLH group, females had significantly better oral health than males, especially concerning endodontic and cariological status (p's = .01 and .02, respectively). Periodontal status differed non-significantly between the XLH and control groups.ConclusionPatients with XLH had a significantly lower oral health status compared to a healthy population especially concerning endodontic conditions. Male patients with XLH had a higher risk of poor oral health compared to female patients with XLH. |
| first_indexed | 2024-04-09T23:31:32Z |
| format | Article |
| id | doaj.art-275307fecc5f4b3eb09e4174433a5820 |
| institution | Directory Open Access Journal |
| issn | 2673-4842 |
| language | English |
| last_indexed | 2024-04-09T23:31:32Z |
| publishDate | 2023-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oral Health |
| spelling | doaj.art-275307fecc5f4b3eb09e4174433a58202023-03-21T04:52:40ZengFrontiers Media S.A.Frontiers in Oral Health2673-48422023-03-01410.3389/froh.2023.10877611087761Dental health of patients with X-linked hypophosphatemia: A controlled studyAmila Larsson0Amila Larsson1Tobias Regnstrand2Pia Skott3Pia Skott4Outi Mäkitie5Outi Mäkitie6Outi Mäkitie7Sigridur Björnsdottir8Sigridur Björnsdottir9Karin Garming-Legert10Department of Dental Medicine, Karolinska Institutet, Huddinge, SwedenPublic Dental Health Service Stockholm AB, Stockholm, SwedenDepartment of Dental Medicine, Karolinska Institutet, Huddinge, SwedenDepartment of Dental Medicine, Karolinska Institutet, Huddinge, SwedenPublic Dental Health Service Stockholm AB, Stockholm, SwedenDepartment of Pediatric Research, Children's Hospital, Pediatric Research Center, University of Helsinki and Helsinki University Hospital, Helsinki, FinlandDepartment of Clinical Genetics, Clinical Genetics, Karolinska University Hospital, Stockholm, SwedenDepartment of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, SwedenDepartment of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, SwedenDepartment of Endocrinology, Metabolism and Diabetes, Karolinska University Hospital, Stockholm, SwedenDepartment of Dental Medicine, Karolinska Institutet, Huddinge, SwedenObjectiveThe present study compared the dental health of patients with X-linked hypophosphatemia (XLH) with healthy age- and gender-matched controls to increase our knowledge of the impact of XLH on oral health.Materials and methodsTwenty-two adult patients with XLH in the Stockholm region of Sweden were referred to the Department of Orofacial Medicine at Karolinska Institutet for an extended clinical and radiological examination. Pre-existing radiologic examinations of 44 healthy age- and gender-matched controls were retrieved from the Department of Oral Radiology, at Karolinska Institutet.ResultsThe 22 patients with XLH (15 females, median age 38 years, range 20–71; 7 males, median age 49 years, range 24–67) had a significantly higher number of root-filled teeth compared to healthy controls (p = .001). In the XLH group, females had significantly better oral health than males, especially concerning endodontic and cariological status (p's = .01 and .02, respectively). Periodontal status differed non-significantly between the XLH and control groups.ConclusionPatients with XLH had a significantly lower oral health status compared to a healthy population especially concerning endodontic conditions. Male patients with XLH had a higher risk of poor oral health compared to female patients with XLH.https://www.frontiersin.org/articles/10.3389/froh.2023.1087761/fulldentalendodonticinfectionsperiodontalXLH |
| spellingShingle | Amila Larsson Amila Larsson Tobias Regnstrand Pia Skott Pia Skott Outi Mäkitie Outi Mäkitie Outi Mäkitie Sigridur Björnsdottir Sigridur Björnsdottir Karin Garming-Legert Dental health of patients with X-linked hypophosphatemia: A controlled study Frontiers in Oral Health dental endodontic infections periodontal XLH |
| title | Dental health of patients with X-linked hypophosphatemia: A controlled study |
| title_full | Dental health of patients with X-linked hypophosphatemia: A controlled study |
| title_fullStr | Dental health of patients with X-linked hypophosphatemia: A controlled study |
| title_full_unstemmed | Dental health of patients with X-linked hypophosphatemia: A controlled study |
| title_short | Dental health of patients with X-linked hypophosphatemia: A controlled study |
| title_sort | dental health of patients with x linked hypophosphatemia a controlled study |
| topic | dental endodontic infections periodontal XLH |
| url | https://www.frontiersin.org/articles/10.3389/froh.2023.1087761/full |
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