Malignant transformation of Madelung’s disease in a patient with a coincidental diagnosis of breast cancer: a case report

<p>Abstract</p> <p>Madelung’s disease or multiple symmetric lipomatosis (MSL) is a rare disorder of unknown etiology which typically presents symmetrically subcutaneous accumulation of non-encapsulated adipose tissue which slowly grows around the neck, upper part of the arms, pelvi...

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Main Authors: Borriello Maddalena, Lucidi Alessandro, Carbone Arnaldo, Iannone Vito, Ferrandina Gabriella
Format: Article
Language:English
Published: BMC 2012-09-01
Series:Diagnostic Pathology
Subjects:
Online Access:http://www.diagnosticpathology.org/content/7/1/116
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author Borriello Maddalena
Lucidi Alessandro
Carbone Arnaldo
Iannone Vito
Ferrandina Gabriella
author_facet Borriello Maddalena
Lucidi Alessandro
Carbone Arnaldo
Iannone Vito
Ferrandina Gabriella
author_sort Borriello Maddalena
collection DOAJ
description <p>Abstract</p> <p>Madelung’s disease or multiple symmetric lipomatosis (MSL) is a rare disorder of unknown etiology which typically presents symmetrically subcutaneous accumulation of non-encapsulated adipose tissue which slowly grows around the neck, upper part of the arms, pelvis, back and thigh. This disease is also frequently associated with hepatopathy, glucose intolerance, hyperuricemia, and malignant tumors of the upper airways. Nevertheless, only one description of malignant transformation of Madelung’s disease has been presented in literature. Here, we report a case of liposarcomatous transformation of Madelung’s disease in a 59-year-old Italian woman with a coincidental diagnosis of breast cancer.</p> <p>Virtual slide</p> <p>The virtual slide for this article can be found here: <url>http://www.diagnosticpathology.diagnomx.eu/vs/3480884087499351</url></p>
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spelling doaj.art-27531cfd50f54ab59dea1e0a4eb182492022-12-22T02:19:20ZengBMCDiagnostic Pathology1746-15962012-09-017111610.1186/1746-1596-7-116Malignant transformation of Madelung’s disease in a patient with a coincidental diagnosis of breast cancer: a case reportBorriello MaddalenaLucidi AlessandroCarbone ArnaldoIannone VitoFerrandina Gabriella<p>Abstract</p> <p>Madelung’s disease or multiple symmetric lipomatosis (MSL) is a rare disorder of unknown etiology which typically presents symmetrically subcutaneous accumulation of non-encapsulated adipose tissue which slowly grows around the neck, upper part of the arms, pelvis, back and thigh. This disease is also frequently associated with hepatopathy, glucose intolerance, hyperuricemia, and malignant tumors of the upper airways. Nevertheless, only one description of malignant transformation of Madelung’s disease has been presented in literature. Here, we report a case of liposarcomatous transformation of Madelung’s disease in a 59-year-old Italian woman with a coincidental diagnosis of breast cancer.</p> <p>Virtual slide</p> <p>The virtual slide for this article can be found here: <url>http://www.diagnosticpathology.diagnomx.eu/vs/3480884087499351</url></p>http://www.diagnosticpathology.org/content/7/1/116Madelung diseaseMalignant degenerationBreast cancer
spellingShingle Borriello Maddalena
Lucidi Alessandro
Carbone Arnaldo
Iannone Vito
Ferrandina Gabriella
Malignant transformation of Madelung’s disease in a patient with a coincidental diagnosis of breast cancer: a case report
Diagnostic Pathology
Madelung disease
Malignant degeneration
Breast cancer
title Malignant transformation of Madelung’s disease in a patient with a coincidental diagnosis of breast cancer: a case report
title_full Malignant transformation of Madelung’s disease in a patient with a coincidental diagnosis of breast cancer: a case report
title_fullStr Malignant transformation of Madelung’s disease in a patient with a coincidental diagnosis of breast cancer: a case report
title_full_unstemmed Malignant transformation of Madelung’s disease in a patient with a coincidental diagnosis of breast cancer: a case report
title_short Malignant transformation of Madelung’s disease in a patient with a coincidental diagnosis of breast cancer: a case report
title_sort malignant transformation of madelung s disease in a patient with a coincidental diagnosis of breast cancer a case report
topic Madelung disease
Malignant degeneration
Breast cancer
url http://www.diagnosticpathology.org/content/7/1/116
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