Kynurenine Monooxygenase Expression and Activity in Human Astrocytomas

Kynurenine Monooxygenase Expression and Activity in Human Astrocytomas

Glioblastoma multiforme (GBM) is the most common and aggressive primary brain tumor. The enzyme indoleamine-2,3-dioxygenase (IDO), which participates in the rate-limiting step of tryptophan catabolism through the kynurenine pathway (KP), is associated with poor prognosis in patients with GBM. The me...

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Bibliographic Details
Main Authors: Gustavo Ignacio Vázquez Cervantes, Benjamín Pineda, Daniela Ramírez Ortega, Alelí Salazar, Dinora Fabiola González Esquivel, Daniel Rembao, Sergio Zavala Vega, Saúl Gómez-Manzo, Gonzalo Pérez de la Cruz, Verónica Pérez de la Cruz
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cells
Subjects:
tryptophan catabolism
kynurenine monooxygenase
glioblastoma
Online Access:https://www.mdpi.com/2073-4409/10/8/2028

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