Kinesin superfamily protein Kif26b links Wnt5a-Ror signaling to the control of cell and tissue behaviors in vertebrates

Kinesin superfamily protein Kif26b links Wnt5a-Ror signaling to the control of cell and tissue behaviors in vertebrates

Wnt5a-Ror signaling constitutes a developmental pathway crucial for embryonic tissue morphogenesis, reproduction and adult tissue regeneration, yet the molecular mechanisms by which the Wnt5a-Ror pathway mediates these processes are largely unknown. Using a proteomic screen, we identify the kinesin...

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Bibliographic Details
Main Authors: Michael W Susman, Edith P Karuna, Ryan C Kunz, Taranjit S Gujral, Andrea V Cantú, Shannon S Choi, Brigette Y Jong, Kyoko Okada, Michael K Scales, Jennie Hum, Linda S Hu, Marc W Kirschner, Ryuichi Nishinakamura, Soichiro Yamada, Diana J Laird, Li-En Jao, Steven P Gygi, Michael E Greenberg, Hsin-Yi Henry Ho
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-09-01
Series:eLife
Subjects:
noncanonical Wnt signaling
Ror
signal transduction
tissue morphogenesis
regulated proteolysis
Kif26b
Online Access:https://elifesciences.org/articles/26509

Internet

https://elifesciences.org/articles/26509

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