New perspectives in coronary heart disease management
The article is devoted to ACE inhibitor therapy in stable coronary heart disease (CHD). The author analyzes the results of multi-center trials on various ACE inhibitors’ efficacy in decreasing risk of all-cause mortality, fatal and non-fatal myocardial infarction, stroke, chronic heart failure in CH...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
«SILICEA-POLIGRAF» LLC
2005-02-01
|
| Series: | Кардиоваскулярная терапия и профилактика |
| Subjects: | |
| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/917 |
| _version_ | 1797882793074622464 |
|---|---|
| author | V. I. Makolkin |
| author_facet | V. I. Makolkin |
| author_sort | V. I. Makolkin |
| collection | DOAJ |
| description | The article is devoted to ACE inhibitor therapy in stable coronary heart disease (CHD). The author analyzes the results of multi-center trials on various ACE inhibitors’ efficacy in decreasing risk of all-cause mortality, fatal and non-fatal myocardial infarction, stroke, chronic heart failure in CHD patients. ACE inhibitor efficacy in CHD is explained by the influence on endothelial dysfunction, thrombosis and inflammation factors, increased bradykinin synthesis and NO-synthase activity. A new trail EUROPA demonstrated that perindopril (8 mg/d) could be recommended to patients with stable CHD. |
| first_indexed | 2024-04-10T03:41:23Z |
| format | Article |
| id | doaj.art-275ad4705a964e7f9f55be2c4efa3944 |
| institution | Directory Open Access Journal |
| issn | 1728-8800 2619-0125 |
| language | Russian |
| last_indexed | 2024-04-10T03:41:23Z |
| publishDate | 2005-02-01 |
| publisher | «SILICEA-POLIGRAF» LLC |
| record_format | Article |
| series | Кардиоваскулярная терапия и профилактика |
| spelling | doaj.art-275ad4705a964e7f9f55be2c4efa39442023-03-13T07:23:11Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252005-02-01419095632New perspectives in coronary heart disease managementV. I. Makolkin0Московская медицинская академия имени И.М.Сеченова, МоскваThe article is devoted to ACE inhibitor therapy in stable coronary heart disease (CHD). The author analyzes the results of multi-center trials on various ACE inhibitors’ efficacy in decreasing risk of all-cause mortality, fatal and non-fatal myocardial infarction, stroke, chronic heart failure in CHD patients. ACE inhibitor efficacy in CHD is explained by the influence on endothelial dysfunction, thrombosis and inflammation factors, increased bradykinin synthesis and NO-synthase activity. A new trail EUROPA demonstrated that perindopril (8 mg/d) could be recommended to patients with stable CHD.https://cardiovascular.elpub.ru/jour/article/view/917ишемическая болезнь сердцафакторы рискалечениеингибиторы ангиотензин-превращающего фермента |
| spellingShingle | V. I. Makolkin New perspectives in coronary heart disease management Кардиоваскулярная терапия и профилактика ишемическая болезнь сердца факторы риска лечение ингибиторы ангиотензин-превращающего фермента |
| title | New perspectives in coronary heart disease management |
| title_full | New perspectives in coronary heart disease management |
| title_fullStr | New perspectives in coronary heart disease management |
| title_full_unstemmed | New perspectives in coronary heart disease management |
| title_short | New perspectives in coronary heart disease management |
| title_sort | new perspectives in coronary heart disease management |
| topic | ишемическая болезнь сердца факторы риска лечение ингибиторы ангиотензин-превращающего фермента |
| url | https://cardiovascular.elpub.ru/jour/article/view/917 |
| work_keys_str_mv | AT vimakolkin newperspectivesincoronaryheartdiseasemanagement |