Crystal structure of 4-bromo-N-(propylcarbamoyl)benzenesulfonamide
The title compound, C10H13BrN2O3S, 1, contains a sulfonyl urea moiety, which possesses potential therapeutic functions (e.g., anti-diabetic and herbicidal). The geometry of 1 is similar to its closely related analogues, chlorpropamide and tolbutamide. This compound crystallizes in the monoclinic spa...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
International Union of Crystallography
2022-05-01
|
| Series: | Acta Crystallographica Section E: Crystallographic Communications |
| Subjects: | |
| Online Access: | http://scripts.iucr.org/cgi-bin/paper?S2056989022003723 |
| _version_ | 1818029254236962816 |
|---|---|
| author | Mustafa Bookwala Saloni Patel Patrick T. Flaherty Peter L. D. Wildfong |
| author_facet | Mustafa Bookwala Saloni Patel Patrick T. Flaherty Peter L. D. Wildfong |
| author_sort | Mustafa Bookwala |
| collection | DOAJ |
| description | The title compound, C10H13BrN2O3S, 1, contains a sulfonyl urea moiety, which possesses potential therapeutic functions (e.g., anti-diabetic and herbicidal). The geometry of 1 is similar to its closely related analogues, chlorpropamide and tolbutamide. This compound crystallizes in the monoclinic space group C2/c, having one molecule in its asymmetric unit. The crystal structure of 1, recorded at 296 K, shows intermolecular N—H...O and C—H...O-type infinite hydrogen-bonded chains involving the sulfonyl urea moiety. Hirshfeld surface analysis and the two-dimensional fingerprint plots confirmed hydrogen bonding as the dominant feature in the crystal packing. |
| first_indexed | 2024-12-10T05:16:46Z |
| format | Article |
| id | doaj.art-275c0a7004734184b07f0e20ec05403e |
| institution | Directory Open Access Journal |
| issn | 2056-9890 |
| language | English |
| last_indexed | 2024-12-10T05:16:46Z |
| publishDate | 2022-05-01 |
| publisher | International Union of Crystallography |
| record_format | Article |
| series | Acta Crystallographica Section E: Crystallographic Communications |
| spelling | doaj.art-275c0a7004734184b07f0e20ec05403e2022-12-22T02:00:56ZengInternational Union of CrystallographyActa Crystallographica Section E: Crystallographic Communications2056-98902022-05-0178548548910.1107/S2056989022003723mw2187Crystal structure of 4-bromo-N-(propylcarbamoyl)benzenesulfonamideMustafa Bookwala0Saloni Patel1Patrick T. Flaherty2Peter L. D. Wildfong3Graduate School of Pharmaceutical Sciences, Duquesne University, 600 Forbes Avenue, Pittsburgh, PA 15282, USAGraduate School of Pharmaceutical Sciences, Duquesne University, 600 Forbes Avenue, Pittsburgh, PA 15282, USAGraduate School of Pharmaceutical Sciences, Duquesne University, 600 Forbes Avenue, Pittsburgh, PA 15282, USAGraduate School of Pharmaceutical Sciences, Duquesne University, 600 Forbes Avenue, Pittsburgh, PA 15282, USAThe title compound, C10H13BrN2O3S, 1, contains a sulfonyl urea moiety, which possesses potential therapeutic functions (e.g., anti-diabetic and herbicidal). The geometry of 1 is similar to its closely related analogues, chlorpropamide and tolbutamide. This compound crystallizes in the monoclinic space group C2/c, having one molecule in its asymmetric unit. The crystal structure of 1, recorded at 296 K, shows intermolecular N—H...O and C—H...O-type infinite hydrogen-bonded chains involving the sulfonyl urea moiety. Hirshfeld surface analysis and the two-dimensional fingerprint plots confirmed hydrogen bonding as the dominant feature in the crystal packing.http://scripts.iucr.org/cgi-bin/paper?S2056989022003723bromopropamidecrystal structuresingle-crystal xrdstructural analogue |
| spellingShingle | Mustafa Bookwala Saloni Patel Patrick T. Flaherty Peter L. D. Wildfong Crystal structure of 4-bromo-N-(propylcarbamoyl)benzenesulfonamide Acta Crystallographica Section E: Crystallographic Communications bromopropamide crystal structure single-crystal xrd structural analogue |
| title | Crystal structure of 4-bromo-N-(propylcarbamoyl)benzenesulfonamide |
| title_full | Crystal structure of 4-bromo-N-(propylcarbamoyl)benzenesulfonamide |
| title_fullStr | Crystal structure of 4-bromo-N-(propylcarbamoyl)benzenesulfonamide |
| title_full_unstemmed | Crystal structure of 4-bromo-N-(propylcarbamoyl)benzenesulfonamide |
| title_short | Crystal structure of 4-bromo-N-(propylcarbamoyl)benzenesulfonamide |
| title_sort | crystal structure of 4 bromo n propylcarbamoyl benzenesulfonamide |
| topic | bromopropamide crystal structure single-crystal xrd structural analogue |
| url | http://scripts.iucr.org/cgi-bin/paper?S2056989022003723 |
| work_keys_str_mv | AT mustafabookwala crystalstructureof4bromonpropylcarbamoylbenzenesulfonamide AT salonipatel crystalstructureof4bromonpropylcarbamoylbenzenesulfonamide AT patricktflaherty crystalstructureof4bromonpropylcarbamoylbenzenesulfonamide AT peterldwildfong crystalstructureof4bromonpropylcarbamoylbenzenesulfonamide |