Hepatitis B virus infection combined with nonalcoholic fatty liver disease: Interaction and prognosis
Hepatitis B virus (HBV) infection is still one kind of the infectious diseases that seriously threaten human health. Nonalcoholic fatty liver disease (NAFLD) has become the most common chronic liver disease worldwide. HBV infection complicated with NAFLD is increasingly common. This review mainly de...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-01-01
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| Series: | Heliyon |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844023003201 |
| _version_ | 1811173267854065664 |
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| author | Lili Liu Hong Li Yang Zhang Jing Zhang Zhenhuan Cao |
| author_facet | Lili Liu Hong Li Yang Zhang Jing Zhang Zhenhuan Cao |
| author_sort | Lili Liu |
| collection | DOAJ |
| description | Hepatitis B virus (HBV) infection is still one kind of the infectious diseases that seriously threaten human health. Nonalcoholic fatty liver disease (NAFLD) has become the most common chronic liver disease worldwide. HBV infection complicated with NAFLD is increasingly common. This review mainly describes the interaction between HBV infection and NAFLD, the interaction between steatosis and antiviral drugs, and the prognosis of HBV infection complicated with NAFLD. Most studies suggest that HBV infection may reduce the incidence of NAFLD. NAFLD can promote the spontaneous clearance of hepatitis B surface antigen (HBsAg), but whether it affects antiviral efficacy has been reported inconsistently. HBV infection combined with NAFLD can promote the progression of liver fibrosis, especially in patients with severe steatosis. The outcome of HBV infection combined with NAFLD predisposing to the progression of HCC remains controversial. |
| first_indexed | 2024-04-10T17:45:06Z |
| format | Article |
| id | doaj.art-275c87170ee3498c8bc5d5dc81683006 |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-04-10T17:45:06Z |
| publishDate | 2023-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-275c87170ee3498c8bc5d5dc816830062023-02-03T05:00:28ZengElsevierHeliyon2405-84402023-01-0191e13113Hepatitis B virus infection combined with nonalcoholic fatty liver disease: Interaction and prognosisLili Liu0Hong Li1Yang Zhang2Jing Zhang3Zhenhuan Cao4The Third Unit, Department of Hepatology, Beijing Youan Hospital, Capital Medical University, Beijing, ChinaThe Third Unit, Department of Hepatology, Beijing Youan Hospital, Capital Medical University, Beijing, ChinaBiomedical Information Center, Beijing Youan Hospital, Capital Medical University, Beijing, ChinaThe Third Unit, Department of Hepatology, Beijing Youan Hospital, Capital Medical University, Beijing, China; Corresponding author.The Third Unit, Department of Hepatology, Beijing Youan Hospital, Capital Medical University, Beijing, China; Corresponding author.Hepatitis B virus (HBV) infection is still one kind of the infectious diseases that seriously threaten human health. Nonalcoholic fatty liver disease (NAFLD) has become the most common chronic liver disease worldwide. HBV infection complicated with NAFLD is increasingly common. This review mainly describes the interaction between HBV infection and NAFLD, the interaction between steatosis and antiviral drugs, and the prognosis of HBV infection complicated with NAFLD. Most studies suggest that HBV infection may reduce the incidence of NAFLD. NAFLD can promote the spontaneous clearance of hepatitis B surface antigen (HBsAg), but whether it affects antiviral efficacy has been reported inconsistently. HBV infection combined with NAFLD can promote the progression of liver fibrosis, especially in patients with severe steatosis. The outcome of HBV infection combined with NAFLD predisposing to the progression of HCC remains controversial.http://www.sciencedirect.com/science/article/pii/S2405844023003201Nonalcoholic fatty liver diseaseHBV infectionAntiviral efficacyLiver fibrosisHepatocellular carcinoma |
| spellingShingle | Lili Liu Hong Li Yang Zhang Jing Zhang Zhenhuan Cao Hepatitis B virus infection combined with nonalcoholic fatty liver disease: Interaction and prognosis Heliyon Nonalcoholic fatty liver disease HBV infection Antiviral efficacy Liver fibrosis Hepatocellular carcinoma |
| title | Hepatitis B virus infection combined with nonalcoholic fatty liver disease: Interaction and prognosis |
| title_full | Hepatitis B virus infection combined with nonalcoholic fatty liver disease: Interaction and prognosis |
| title_fullStr | Hepatitis B virus infection combined with nonalcoholic fatty liver disease: Interaction and prognosis |
| title_full_unstemmed | Hepatitis B virus infection combined with nonalcoholic fatty liver disease: Interaction and prognosis |
| title_short | Hepatitis B virus infection combined with nonalcoholic fatty liver disease: Interaction and prognosis |
| title_sort | hepatitis b virus infection combined with nonalcoholic fatty liver disease interaction and prognosis |
| topic | Nonalcoholic fatty liver disease HBV infection Antiviral efficacy Liver fibrosis Hepatocellular carcinoma |
| url | http://www.sciencedirect.com/science/article/pii/S2405844023003201 |
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