Potent and long-lasting humoral and cellular immunity against varicella zoster virus induced by mRNA-LNP vaccine

Abstract Varicella zoster virus (VZV) is a highly contagious human herpes virus responsible for causing chickenpox (varicella) and shingles (herpes zoster). Despite the approval of a highly effective vaccine, Shingrix®, the global incidence of herpes zoster is increasing and the economic burden to t...

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Bibliographic Details
Main Authors: Anannya Bhattacharya, Lonzaric Jan, Olga Burlak, Jilong Li, Ghanshyam Upadhyay, Katherine Williams, Jinhui Dong, Harrison Rohrer, Michelle Pynn, Andrew Simon, Nathan Kuhlmann, Sergei Pustylnikov, Mariane B. Melo, Antu K. Dey
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-024-00865-5