Interferon-Alpha 2-a and Its Dual Effect in Treating Two Diseases (Hepatitis C and Polycythemia Vera)

Hepatitis C and polycythemia vera (PV) co-existence is not rare; it has been reported in the literature. Treatment with interferon (IFN) has been used to treat both conditions; however, the use of IFN in concomitant hepatitis C infection with PV and its outcome are rarely described in the literature...

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Main Authors: Hawraa Shwaylia, Elrazi Ali, Mohamed A. Yassin
Format: Article
Language:English
Published: Karger Publishers 2021-06-01
Series:Case Reports in Oncology
Subjects:
Online Access:https://www.karger.com/Article/FullText/515782
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author Hawraa Shwaylia
Elrazi Ali
Mohamed A. Yassin
author_facet Hawraa Shwaylia
Elrazi Ali
Mohamed A. Yassin
author_sort Hawraa Shwaylia
collection DOAJ
description Hepatitis C and polycythemia vera (PV) co-existence is not rare; it has been reported in the literature. Treatment with interferon (IFN) has been used to treat both conditions; however, the use of IFN in concomitant hepatitis C infection with PV and its outcome are rarely described in the literature. Here, we report a 56-years-old male patient with hepatitis C virus infection and PV, who was treated with IFN for his chronic hepatitis C, which resulted in significant improvement of HB as well as normalization of his bone marrow and eradication of the clone (Jak2 V617F).
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spelling doaj.art-275f84ddf89a47b59551ac8183df57332022-12-21T17:59:58ZengKarger PublishersCase Reports in Oncology1662-65752021-06-0114284584810.1159/000515782515782Interferon-Alpha 2-a and Its Dual Effect in Treating Two Diseases (Hepatitis C and Polycythemia Vera)Hawraa Shwaylia0Elrazi Ali1Mohamed A. Yassin2Department of Medical Oncology, Hamad Medical Corporation, Doha, QatarInternal Medicine Department, Hamad Medical Corporation, Doha, QatarDepartment of Medical Oncology, Hamad Medical Corporation, Doha, QatarHepatitis C and polycythemia vera (PV) co-existence is not rare; it has been reported in the literature. Treatment with interferon (IFN) has been used to treat both conditions; however, the use of IFN in concomitant hepatitis C infection with PV and its outcome are rarely described in the literature. Here, we report a 56-years-old male patient with hepatitis C virus infection and PV, who was treated with IFN for his chronic hepatitis C, which resulted in significant improvement of HB as well as normalization of his bone marrow and eradication of the clone (Jak2 V617F).https://www.karger.com/Article/FullText/515782polycythemia verahepatitis chepatitisinterferon
spellingShingle Hawraa Shwaylia
Elrazi Ali
Mohamed A. Yassin
Interferon-Alpha 2-a and Its Dual Effect in Treating Two Diseases (Hepatitis C and Polycythemia Vera)
Case Reports in Oncology
polycythemia vera
hepatitis c
hepatitis
interferon
title Interferon-Alpha 2-a and Its Dual Effect in Treating Two Diseases (Hepatitis C and Polycythemia Vera)
title_full Interferon-Alpha 2-a and Its Dual Effect in Treating Two Diseases (Hepatitis C and Polycythemia Vera)
title_fullStr Interferon-Alpha 2-a and Its Dual Effect in Treating Two Diseases (Hepatitis C and Polycythemia Vera)
title_full_unstemmed Interferon-Alpha 2-a and Its Dual Effect in Treating Two Diseases (Hepatitis C and Polycythemia Vera)
title_short Interferon-Alpha 2-a and Its Dual Effect in Treating Two Diseases (Hepatitis C and Polycythemia Vera)
title_sort interferon alpha 2 a and its dual effect in treating two diseases hepatitis c and polycythemia vera
topic polycythemia vera
hepatitis c
hepatitis
interferon
url https://www.karger.com/Article/FullText/515782
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AT elraziali interferonalpha2aanditsdualeffectintreatingtwodiseaseshepatitiscandpolycythemiavera
AT mohamedayassin interferonalpha2aanditsdualeffectintreatingtwodiseaseshepatitiscandpolycythemiavera