EIF4A3-mediated circPRKCI expression promotes triple-negative breast cancer progression by regulating WBP2 and PI3K/AKT signaling pathway
Abstract Triple-negative breast cancer (TNBC) is known as a highly aggressive subtype of BC due to high rate of recurrence and metastasis, poor prognosis and lacking of effective targeted therapies. Circular RNAs (circRNAs) have been reported to participate in the progression of TNBC. In this study,...
Main Authors: | Xuehui Wang, Hongming Song, Lin Fang, Tianqi Wu |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2022-03-01
|
Series: | Cell Death Discovery |
Online Access: | https://doi.org/10.1038/s41420-022-00892-y |
Similar Items
-
Prognostic and clinical value of circPRKCI expression in diverse human cancers
by: Zhongyue Liu, et al.
Published: (2024-01-01) -
WBP2 Downregulation Inhibits Proliferation by Blocking YAP Transcription and the EGFR/PI3K/Akt Signaling Pathway in Triple Negative Breast Cancer
by: Hongming Song, et al.
Published: (2018-08-01) -
Biosynthesis of UDP-GlcNAc(3NAc)A by WbpB, WbpE, and WbpD: Enzymes in the Wbp Pathway Responsible for O-antigen Assembly in Pseudomonas aeruginosa PAO1
by: Larkin, Angelyn, et al.
Published: (2012) -
Thioguanine Induces Apoptosis in Triple-Negative Breast Cancer by Regulating PI3K–AKT Pathway
by: Daoyu Zhang, et al.
Published: (2020-10-01) -
CircWAC induces chemotherapeutic resistance in triple-negative breast cancer by targeting miR-142, upregulating WWP1 and activating the PI3K/AKT pathway
by: Lei Wang, et al.
Published: (2021-03-01)